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中文名 | 依喜替康甲磺酸盐 |
英文名 | Exatecan mesylate |
别名 | 依替喜康 甲磺酸伊喜替康 甲磺酸依喜替康 甲磺酸依他替康 依沙替康甲磺酸盐 依喜替康甲磺酸盐 (1S,9S)-1-氨基-9-乙基-5-氟-9-羟基-4-甲基-2,3,12,15-四氢苯并[DE]吡喃并[3,4,6,7]吲哚并[1,2-B]喹啉-10,13(1H,9H)-二酮 甲磺酸盐 |
CAS | 169869-90-3 |
EINECS | |
化学式 | C25H26FN3O7S |
分子量 | 531.5532 |
inchi | |
包装信息 | 500 mg |
价格 | $298 |
产品描述 | 依喜替康甲磺酸盐 Exatecan mesylate is a semisynthetic, water-soluble derivative of camptothecin with antineoplastic activity. Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting the religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death. This agent does not require enzymatic activation and exhibits greater potency than camptothecin and other camptothecin analogs. |
产品链接 | http://www.bocsci.com/product/exatecan-mesylate-cas-169869-90-3-60840.html |
更新日期 | 2025-04-30 11:27:47 |