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| 中文名 | 阿培利司 |
| 英文名 | Alpelisib (BYL719) |
| 别名 | 阿吡利塞;阿培利司;小分子抑制剂;PI3KΑ抑制剂(BYL-719);阿博利布(阿培利斯)BYL-719;(2S)-N1-[4-甲基-5-[2-(2,2,2-三氟-1,1-二甲基乙基)-4-吡啶]-2-噻唑]-1,2-吡咯烷二羧酰胺;(2S)-N1-[4-甲基-5-[2-(2,2,2-三氟-1,1-二甲基乙基)-4-吡啶基]-2-噻唑基]-1,2-吡咯烷二甲酰胺 |
| CAS | 1217486-61-7 |
| EINECS | |
| 化学式 | C19H22F3N5O2S |
| 分子量 | 441.47 |
| inchi | |
| 包装信息 | 100 mg |
| 价格 | $199 |
| 产品描述 | 阿培利司 Alpelisib, also known as BLY719, is an orally bioavailable phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity. PI3K inhibitor BYL719 specifically inhibits PIK3 in the PI3K/AKT kinase (or protein kinase B) signaling pathway, thereby inhibiting the activation of the PI3K signaling pathway. This may result in inhibition of tumor cell growth and survival in susceptible tumor cell populations. Activation of the PI3K signaling pathway is frequently associated with tumorigenesis. Dysregulated PI3K signaling may contribute to tumor resistance to a variety of antineoplastic agents. |
| 产品链接 | http://www.bocsci.com/alpelisib-cas-1217486-61-7-item-457654.html |
| 更新日期 | 2025-04-30 11:27:47 |