1-Aminoindane
1-Aminoindane
CAS: 61949-83-5;34698-41-4
Molecular Formula: C9H11N
1-Aminoindane - Names and Identifiers
| Name | 1-Aminoindane |
| Synonyms | 1-Indanamine 1-Aminoindan 1-Aminoindane indan-1-ylamine 1-AMINOHYDRINDENE 2,3-dihydro-1H-inden-1-amine (1S)-2,3-dihydro-1H-inden-1-aminium (1R)-2,3-dihydro-1H-inden-1-aminium |
| CAS | 61949-83-5 34698-41-4 |
| EINECS | 925-175-9 |
| InChI | InChI=1/C9H11N/c10-9-6-5-7-3-1-2-4-8(7)9/h1-4,9H,5-6,10H2/p+1/t9-/m0/s1 |
1-Aminoindane - Physico-chemical Properties
| Molecular Formula | C9H11N |
| Molar Mass | 133.19 |
| Density | 1.038 |
| Melting Point | 15 ºC |
| Boling Point | 96-97 ºC |
| Flash Point | 94 ºC |
| Water Solubility | insoluble |
| Vapor Presure | 0.0886mmHg at 25°C |
| pKa | 9.21(at 22℃) |
| Refractive Index | 1.561 |
1-Aminoindane - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
1-Aminoindane - Introduction
1-Aminoindane(1-Aminoindane) is an organic compound with the chemical formula C9H9N. It is an amino derivative of indane and has the morphology of a blue solid crystal. The following is a description of the nature, use, preparation and safety information of 1-Aminoindane:
Nature:
1-Aminoindane is a combustible solid. It has a slight ammonia odor at room temperature and is soluble in many organic solvents, such as alcohols, ethers and hydrocarbons. It has low solubility and is easy to crystallize.
Use:
1-Aminoindane has certain applications in the field of medicine. It is often used as a research reagent for antidepressants and in the synthesis of other pharmaceutical compounds. In addition, due to its stimulating and hallucinogenic properties, it has also been abused as a stimulant.
Preparation Method:
A common method for preparing 1-Aminoindane is through an N-nitroindane reduction reaction. First, indane is nitrated to give N-nitroindane, which is reduced to 1-Aminoindane with a reducing agent (e. g., tin) under appropriate conditions.
Safety Information:
The toxicity and carcinogenicity of 1-Aminoindane have not been fully studied, so care should be taken when using it. It may be irritating to the skin, eyes, and breathing. Contact and inhalation should be avoided. At the same time, it is a precursor for the production of drugs and therefore needs to be properly handled and stored in accordance with regulations to prevent abuse and illicit use. Proper laboratory operation and safety procedures should be followed when using and handling 1-Aminoindane.
Nature:
1-Aminoindane is a combustible solid. It has a slight ammonia odor at room temperature and is soluble in many organic solvents, such as alcohols, ethers and hydrocarbons. It has low solubility and is easy to crystallize.
Use:
1-Aminoindane has certain applications in the field of medicine. It is often used as a research reagent for antidepressants and in the synthesis of other pharmaceutical compounds. In addition, due to its stimulating and hallucinogenic properties, it has also been abused as a stimulant.
Preparation Method:
A common method for preparing 1-Aminoindane is through an N-nitroindane reduction reaction. First, indane is nitrated to give N-nitroindane, which is reduced to 1-Aminoindane with a reducing agent (e. g., tin) under appropriate conditions.
Safety Information:
The toxicity and carcinogenicity of 1-Aminoindane have not been fully studied, so care should be taken when using it. It may be irritating to the skin, eyes, and breathing. Contact and inhalation should be avoided. At the same time, it is a precursor for the production of drugs and therefore needs to be properly handled and stored in accordance with regulations to prevent abuse and illicit use. Proper laboratory operation and safety procedures should be followed when using and handling 1-Aminoindane.
Last Update：2024-04-09 21:11:58
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