2. Apoptosis Metabolic Enzyme/Protease Immunology/Inflammation NF-κB
  3. Apoptosis Reactive Oxygen Species (ROS) Caspase Mitochondrial Metabolism
  4. 4-Methylthiazole

4-Methylthiazole 是一种凋亡 (Apoptosis) 触发剂。4-Methylthiazole 可显著降低 CD45 和 CD123 表面标志物的表达，增加 ROS 水平和 Caspase-3 蛋白水平。4-Methylthiazole 可诱导凋亡和线粒体功能障碍 (mitochondrial disruption)。4-Methylthiazole 可用于急性早幼粒细胞白血病的研究。

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4-Methylthiazole

4-Methylthiazole Chemical Structure

CAS No. : 693-95-8

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规格 价格 是否有货 数量
500 mg ￥180
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1 g ￥312
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4-Methylthiazole 相关抗体

Top Publications Citing Use of Products

查看 Caspase 亚型特异性产品:

查看所有亚型
Caspase 1 Caspase 2 Caspase 3 Caspase 4 Caspase 5 Caspase 6 Caspase 7 Caspase 8 Caspase 9 Caspase 10 Caspase 12 Caspase Caspase 11 Caspase-13

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

4-Methylthiazole is an Apoptosis trigger. 4-Methylthiazole markedly reduces CD45 and CD123 surface markers, increases ROS levels, Caspase-3 protein levels. 4-Methylthiazole triggers Apoptosis and mitochondrial disruption. 4-Methylthiazole can be used in the research of acute promyelocytic leukemia[1].

IC50 & Target[1]

Caspase-3

 

体外研究
(In Vitro)

用作医药和香料的中间体

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

4-Methylthiazole 相关抗体:
分子量

99.15

Formula

C4H5NS
CAS 号
性状

液体

结构分类
初始来源

Rhizopus suinus
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
纯度 & 产品资料
参考文献

4-Methylthiazole 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

4-Methylthiazole693-95-8ApoptosisReactive Oxygen Species (ROS)CaspaseMitochondrial MetabolismHL-60Inhibitorinhibitorinhibit

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