1. 天然产物
  2. 植物 酚类 酮、醛、酸
  3. 芸香科
  4. 山油柑
  5. Acrovestone

Acrovestone (compound 4) 是一种 Acronychia 型苯乙酮二聚体,是选择性抗癌剂。Acrovestone 对 A2058 黑素瘤细胞和 DU145 前列腺癌细胞的 IC50 值分别为 0.38 μM 和 0.93 μM。Acrovestone 对正常人真皮成纤维细胞 (NHDF) 的抑制活性较低,IC50 >5 μM。Acrovestone 可用于前列腺癌和黑色素瘤相关的抗癌研究。Acrovestone 能够从 Acronychia pedunculata (山油柑) 的树干树皮中天然提取得到。

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Acrovestone

Acrovestone Chemical Structure

CAS No. : 24177-16-0

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  • 生物活性

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生物活性

Acrovestone (compound 4) is an Acronychia-type acetophenone dimer and a selective anticancer agent. Acrovestone has IC50 values ??of 0.38 μM and 0.93 μM against A2058 melanoma cells and DU145 prostate cancer cells, respectively. Acrovestone shows low inhibitory activity against normal human dermal fibroblasts (NHDF), with an IC50 >5 μM. Acrovestone can be used in anticancer research related to prostate cancer and melanoma. Acrovestone can be naturally extracted from the trunk bark of Acronychia pedunculata[1].

分子量

554.67

Formula

C32H42O8

CAS 号
中文名称

包山油柑酚

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

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参考文献
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Acrovestone
目录号:
HY-N16691
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