2. Others Anti-infection
  3. Drug Derivative Fungal
  4. Antifungal agent 141

Antifungal agent 141，一种 Phenoxazine (HY-34463) 衍生物，是一种抗真菌剂。Antifungal agent 141 对新型隐球菌 (Cryptococcus neoformans) 和白色念珠菌 (Candida albicans) 表现出强大的抗真菌活性，其 MIC 值分别为 2 和 4 µg/mL。Antifungal agent 141 可用于隐球菌性脑膜炎的研究。

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Antifungal agent 141

Antifungal agent 141 Chemical Structure

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Antifungal agent 141 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antifungal agent 141, a Phenoxazine (HY-34463) derivative, is an antifungal agent. Antifungal agent shows potent antifungal activity in Cryptococcus neoformans and Candida albicans with MIC values of 2 and 4 µg/mL. Antifungal agent 141 can be used for the research of cryptococcal meningitis[1].

体外研究
(In Vitro)

Antifungal agent 141 (Compound 61) 在新型隐球菌 (Cryptococcus neoformans) 和白色念珠菌 (Candida albicans) 中表现出强效的抗真菌活性，其 MIC 值为 2 和 4 µg/mL[1]。
Antifungal agent 141 对血清素受体 (如 5-HT1A/1B/1D/2A) 和多巴胺受体 (如 D1/D2/D3) 的亲和力较低，其 Ki 值均大于 500 nM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antifungal agent 141 相关抗体:
体内研究
(In Vivo)

Antifungal agent 141 (Compound 61) (50 mg/kg，腹腔注射，每日 1 次，连续 3 天) 在播散性隐球菌病的小鼠模型中未减少脑部真菌负荷[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

497.55

Formula

C28H30F3N3O2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antifungal agent 141 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antifungal agent 141Antifungal agent141Antifungal agent-141Drug DerivativeFungalDrug derivativeCryptococcus neoformansPhenoxazineAntifungalCandida albicans5-HTdopamine receptorInhibitorinhibitorinhibit

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