2. Apoptosis PI3K/Akt/mTOR MAPK/ERK Pathway Stem Cell/Wnt JAK/STAT Signaling
  3. Apoptosis Akt ERK STAT Ribosomal S6 Kinase (RSK)
  4. Apoptosis inducer 55

Apoptosis inducer 55 (Compound 10) 是一种凋亡 (Apoptosis) 诱导剂。Apoptosis inducer 55 通过内源性途径快速诱导细胞凋亡。Apoptosis inducer 55 能有效抑制多种信号通路，包括 AKT、ERK1/2、STAT1、STAT3 和 S6K。Apoptosis inducer 55 对黑色素瘤具有抗癌活性。

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Apoptosis inducer 55

Apoptosis inducer 55 Chemical Structure

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Apoptosis inducer 55 相关抗体

Top Publications Citing Use of Products

查看 Akt 亚型特异性产品:

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Akt Akt1 Akt2 Akt3

查看 ERK 亚型特异性产品:

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ERK ERK1 ERK2 ERK5 ERK8

查看 STAT 亚型特异性产品:

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STAT3 STAT5 STAT6 STAT1

查看 Ribosomal S6 Kinase (RSK) 亚型特异性产品:

查看所有亚型
p70S6K RSK2 RSK3 RSK4

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Apoptosis inducer 55 (Compound 10) is an Apoptosis inducer. Apoptosis inducer 55 induces rapid apoptosis via the intrinsic pathway. Apoptosis inducer 55 potently inhibits several signaling cascades including AKT, ERK1/2, STAT1, STAT3, and S6K. Apoptosis inducer 55 has anti-cancer activity against melanoma[1].

IC50 & Target[1]

ERK1

 

ERK2

 

STAT3

 

STAT1

 

分子量

421.49

Formula

C27H23N3O2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Apoptosis inducer 55 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Apoptosis inducer 55Apoptosis inducer55Apoptosis inducer-55ApoptosisAktERKSTATRibosomal S6 Kinase (RSK)PKBProtein kinase BExtracellular signal regulated kinasesS6Kanti-cancermelanomaInhibitorinhibitorinhibit

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