2. Others
  3. Drug Intermediate
  4. Avizafone

Avizafone (Pro-diazepam) 是地西泮的前体药物，具有抗惊厥作用。Avizafone 可用作神经毒剂中毒的解毒剂。在体内，Avizafone 可被氨基肽酶迅速水解，生成赖氨酸和地西泮。Avizafone 的研究领域包括神经系统疾病，例如癫痫。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Avizafone

Avizafone Chemical Structure

CAS No. : 65617-86-9

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Avizafone 的其他形式现货产品:

Customer Review

Other Forms of Avizafone:

Avizafone 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Avizafone (Pro-diazepam), a pro-drug of Diazepam, is an anticonvulsant agent. Avizafone can be used as an antidote of nerve agent poisoning. In vivo, Avizafone is rapidly hydrolyzed by aminopeptidase to produce lysine and diazepam. Avizafone has research areas including neurological disease, such as epilepsy[1][2][3].

体内研究
(In Vivo)

Avizafone (3.5 mg/kg；肌内注射；单次给药) 可预防 Charles River 豚鼠 (梭曼中毒) 的癫痫发作、减轻临床症状、消除 24 小时死亡率并缓解脑损伤 (24 小时死亡率为 0%)[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Guinea pigs (300-350 g)[2]
Dosage: 3.5 mg/kg
Administration: i.m.; single dose
Result: Reduced clinical sign severity to score 1 vs. 3 in controls, achieved 0% 24-hour mortality, prevented seizures in 0/8 animals, reduced necrosis to 3/8 animals vs. 4/4 in controls, eliminated perivascular cuffs and edema, prevented seizures in 0/8 animals vs. 4/8 with diazepam, eliminated brain lesions, and showed no significant respiratory parameter modifications.
分子量

430.93

Formula

C22H27ClN4O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Avizafone 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Avizafone65617-86-9Pro-diazepamDrug IntermediateDrug Iintermediateneurological diseaseguinea pigspralidoximesomanCharles River guinea pigssoman poisoningdiazepamsoman neurotoxicityatropinerespiratory distressInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Avizafone
目录号：
HY-123193
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z