1. PROTAC Epigenetics
  2. Ligands for Target Protein for PROTAC Epigenetic Reader Domain
  3. BRD4 ligand 14

BRD4 ligand 14 (Compound Y47) 是一种 BRD4 抑制剂。BRD4 ligand 14 通过抑制 BRD4,对急性髓系白血病表现出轻微的抗癌特性。BRD4 ligand 14 可作为靶蛋白配体 (Ligands for Target Protein for PROTAC),用于开发设计 PROTAC BRD4 的降解剂,例如 PROTAC BRD4 Degrader-42 (HY-180150)。

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BRD4 ligand 14

BRD4 ligand 14 Chemical Structure

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

BRD4 ligand 14 (Compound Y47) is a BRD4 inhibitor. BRD4 ligand 14 exhibits mild anticancer properties against acute myeloid leukemia by inhibiting BRD4. BRD4 ligand 14 can also be used as a ligand for target protein for PROTAC in the development and design of PROTAC BRD4 degraders, such as PROTAC BRD4 Degrader-42 (HY-180150)[1].

IC50 & Target[1]

BRD4

 

分子量

403.43

Formula

C23H21N3O4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
BRD4 ligand 14
目录号:
HY-180152
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