2. Others Immunology/Inflammation NF-κB Apoptosis
  3. Drug Derivative IFNAR NF-κB Interleukin Related TNF Receptor
  4. CDN-3

CDN-3 (Compound 10) 是一种环二核苷酸衍生物。CDN-3 能够刺激 IFN-β 产生，激活 IRF-3 和 NF-κB 通路，并诱导 I 型干扰素以及 IL-6、TNF-α 等促炎因子的产生。CDN-3 可抑制癌细胞的增殖。CDN-3 可用于结肠癌的研究。

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CDN-3

CDN-3 Chemical Structure

CAS No. : 2768839-23-0

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CDN-3 相关抗体

Top Publications Citing Use of Products

查看 NF-κB 亚型特异性产品:

查看所有亚型
NF-κB NF-κB1/p50 RelA/p65 RelB c-Rel

查看 Interleukin Related 亚型特异性产品:

查看所有亚型
IL-1 IL-2 IL-3 IL-4 IL-5 IL-6 IL-8 IL-10 IL-12 IL-13 IL-15 IL-17 IL-23 IL-7 IL-33 IL-22 IL-18

查看 TNF Receptor 亚型特异性产品:

查看所有亚型
TNFRSF1A/CD120a TNFRSF3/CD18 TNFRSF4 TNFRSF5/CD40 TNFRSF6/Fas/CD95 TNFRSF7/CD27 TNFRSF8/CD30 TNFRSF9/4-1BB/CD137 TNFRSF12A/TWEAK TNFRSF16/NGF Receptor/CD271 TNFRSF18/GITR/CD357

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CDN-3 (Compound 10) is a cyclic dideoxy nucleotide derivative. CDN-3 can stimulate the production of IFN-β, activate the IRF-3 and NF-κB pathways, and induce the production of type I interferons as well as pro-inflammatory factors such as IL-6 and TNF-α. CDN-3 can inhibit cancer cells proliferation. CDN-3 can be used for research of colon cancer[1].

分子量

742.98

Formula

C20H22ClFN10O10P2S2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

CDN-3 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CDN-32768839-23-0CDN3CDN 3Drug DerivativeIFNARNF-κBInterleukin RelatedTNF ReceptorDrug derivativeInterferon-α/β receptorInterferon-alpha/beta receptor Nuclear factor-κBNuclear factor-kappaBILTumor Necrosis Factor ReceptorTNFRInhibitorinhibitorinhibit

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目录号：
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