1. Others Anti-infection
  2. Drug Intermediate Bacterial
  3. Cyclomarin monomer-1

Cyclomarin monomer-1 (Compound 5),一种环马林 (cyclomarin) 单体,是一种二聚化前体,可形成靶向降解 ClpC1 的 Homo-BacPROTACs。Cyclomarin monomer-1 与结核分枝杆菌 (Mtb) ClpC1 蛋白结合,KD 为 3.5 nM。Cyclomarin monomer-1 对 Mtb H37Rv 标准菌株的 MIC 为 1.6 μM。Cyclomarin monomer-1 可用于 Homo-BacPROTACs 开发的关键中间体。

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Custom Peptide Synthesis

Cyclomarin monomer-1

Cyclomarin monomer-1 Chemical Structure

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Cyclomarin monomer-1 (Compound 5), a cyclomarin monomer, is a pre-dimerization precursor that can form Homo-BacPROTACs targeting the degradation of ClpC1. Cyclomarin monomer-1 binds to the Mtb ClpC1 protein with a KD of 3.5 nM. The MIC of Cyclomarin monomer-1 against the Mtb H37Rv standard strain is 1.6 μM. Cyclomarin monomer-1 can be used as a key intermediate in the development of Homo-BacPROTACs[1].

分子量

941.17

Formula

C51H72N8O9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Cyclomarin monomer-1
目录号:
HY-P11497
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