2. Gene
  3. Ffar4 - free fatty acid receptor 4 Gene

Ffar4 - free fatty acid receptor 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Ffa4; GT01; Pgr4; Gpr120; Gpr129; O3far1; KPG_013

基因 ID: 107221 | 基因类型: protein coding

关于 Ffar4

功能概要

Enables G protein-coupled receptor activity; fatty acid binding activity; and Taste Receptor activity. Involved in several processes, including brown fat cell differentiation; positive regulation of cell communication; and positive regulation of cell differentiation. Acts upstream of or within G protein-coupled receptor signaling pathway and hormone secretion. Located in cilium; endocytic vesicle; and plasma membrane. Is expressed in brown fat; intestine; and liver. Human ortholog(s) of this gene implicated in obesity. Orthologous to human FFAR4 (Free Fatty Acid Receptor 4). [provided by Alliance of Genome Resources, Apr 2022]

Ffar4 基因产物(1)

mRNA Protein Name
NM_181748.2 NP_861413.1 free fatty acid receptor 4
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G protein-coupled receptor activity IDA
IDA: 通过直接分析推断
15619630 MGI
enables fatty acid binding IDA
IDA: 通过直接分析推断
15619630 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
20813258 MGI
enables taste receptor activity IMP
IMP: 通过突变表型推断
20573884 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
15619630 MGI
involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
31761534 MGI
involved in brown fat cell differentiation IMP
IMP: 通过突变表型推断
27853148 MGI
involved in fat cell differentiation IMP
IMP: 通过突变表型推断
22343897 MGI
involved in ghrelin secretion IMP
IMP: 通过突变表型推断
24222669 MGI
acts upstream of or within hormone secretion IDA
IDA: 通过直接分析推断
15619630 MGI
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
15774482 MGI
involved in negative regulation of cytokine production IDA
IDA: 通过直接分析推断
20813258 MGI
acts upstream of or within negative regulation of cytokine production IMP
IMP: 通过突变表型推断
26828067 MGI
involved in negative regulation of inflammatory response IDA
IDA: 通过直接分析推断
20813258 MGI
involved in negative regulation of somatostatin secretion IMP
IMP: 通过突变表型推断
24663807 MGI
involved in phospholipase C-activating G protein-coupled receptor signaling pathway IMP
IMP: 通过突变表型推断
27852822 MGI
involved in positive regulation of ERK1 and ERK2 cascade IMP
IMP: 通过突变表型推断
15774482 MGI
involved in positive regulation of brown fat cell differentiation IMP
IMP: 通过突变表型推断
29343498 MGI
involved in positive regulation of cold-induced thermogenesis IMP
IMP: 通过突变表型推断
27853148 MGI
involved in positive regulation of cytosolic calcium ion concentration IMP
IMP: 通过突变表型推断
27852822 MGI
involved in positive regulation of glucagon secretion IMP
IMP: 通过突变表型推断
24742677 MGI
involved in positive regulation of osteoblast differentiation IMP
IMP: 通过突变表型推断
26365922 MGI
involved in regulation of D-glucose transmembrane transport IDA
IDA: 通过直接分析推断
20813258 MGI
involved in white fat cell differentiation IDA
IDA: 通过直接分析推断
31761534 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cilium IDA
IDA: 通过直接分析推断
31761534 MGI
located in endocytic vesicle IDA
IDA: 通过直接分析推断
15619630 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
15619630 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

free fatty acid receptor 4

G-protein coupled receptor 120

G-protein-coupled receptor GT01

omega-3 fatty acid receptor 1

Ffar4 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Ffar4 Q7TMA4 Arrb2 Mus musculus Q91YI4
Anti Tag CoIP
20813258
种属内
Ffar4 Q7TMA4 Arrb2 Mus musculus Q91YI4
Anti Bait CoIP
20813258
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (8)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-W592871 10-Hydroxy-2-decenoic acid 99.99% 否
HY-114610 13Z,16Z-Docosadienoic acid Agonist 99.00% 否
HY-N3977 Grifolic acid Agonist 98.0% 否
HY-162689 GprA Agonist / 否
HY-164870 FFAR1/FFAR4 agonist-1 Agonist / 否
HY-RS04877 FFAR4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18817 Ffar4 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25307 Ffar4 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ffar4 NCBI NCBI:338557
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