1. Gene
  2. Acta2 - actin alpha 2, smooth muscle, aorta Gene

Acta2 - actin alpha 2, smooth muscle, aorta Gene

种属: Mus musculus

同用名: Actvs; a-SMA; SMAalpha; SMalphaA; alphaSMA; 0610041G09Rik

基因 ID: 11475 | 基因类型: protein coding

关于 Acta2

功能概要

The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in smooth muscle. [provided by RefSeq, Feb 2021]

Acta2 基因产物(1)

mRNA Protein Name
NM_007392.3 NP_031418.1 actin, aortic smooth muscle
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
23055941 MGI
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
21307259 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within regulation of blood pressure IMP
IMP: 通过突变表型推断
11053242 MGI
acts upstream of or within vascular associated smooth muscle contraction IMP
IMP: 通过突变表型推断
11053242 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in actin cytoskeleton IDA
IDA: 通过直接分析推断
17882221 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
17717145 MGI
located in cytoskeleton IDA
IDA: 通过直接分析推断
16989802 MGI
located in motile cilium IDA
IDA: 通过直接分析推断
35087169 MGI
located in smooth muscle contractile fiber IDA
IDA: 通过直接分析推断
18332105 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

actin, aortic smooth muscle

actin, alpha, vascular smooth muscle

alpha-actin-2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Acta2 NCBI NCBI:59