2. Gene
  3. LIX1 - limb and CNS expressed 1 Gene

LIX1 - limb and CNS expressed 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：肢体和中枢神经系统表达 1

种属: Homo sapiens

同用名: Lft; C5orf11

基因 ID: 167410 | 基因类型: protein coding

关于 LIX1

Cytogenetic location: 5q15 Genomic coordinates (GRCh38): 5:97,091,867-97,142,611 (from NCBI)

This gene has 2 transcripts (splice variants), 189 orthologues and 2 paralogues. Biased expression in brain (RPKM 14.2), thyroid (RPKM 2.1) and 1 other tissue.

功能概要

预计参与自噬体成熟。预计在细胞质中有活性。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to be involved in autophagosome maturation. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

LIX1 基因产物(1)

mRNA Protein Name
NM_153234.5 NP_694966.3 protein limb expression 1 homolog
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

LIX1 蛋白结构

LIX1

LIX1: Limb expression 1 (10 - 259)

  • 0
  • 100
  • 200
  • 282 a.a.
蛋白主名 其他名称

protein limb expression 1 homolog

Lix1 homolog

LIX1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
LIX1 Q8N485 JPH3 Homo sapiens Q8WXH2
Validated Y2H
32814053
种属内
LIX1 Q8N485 JPH3 Homo sapiens Q8WXH2
Y2H Array
32814053
种属内
LIX1 Q8N485 JPH3 Homo sapiens Q8WXH2
Y2H Pooling
32814053
种属内
LIX1 Q8N485 FAM110A Homo sapiens Q9BQ89
Validated Y2H
32296183
种属内
LIX1 Q8N485 TSACC Homo sapiens Q96A04
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
3-Methylglutaconic Aciduria, Type Iv

3-Methylglutaconic Aciduria Type 4

Mga4

MGCA4

3-Methylglutaconic Aciduria Type Iv

Mga, Type Iv

Mga Type Iv

Not Otherwise Specified 3-Mga-Uria Type

3 Alpha Methylglutaconic Aciduria Type Iv

3 Methylglutaconic Aciduria Type Iv
Cutaneous Anthrax

Anthrax, Skin Type

Skin Anthrax
3-Methylglutaconic Aciduria, Type I

3-Methylglutaconyl-Coa Hydratase Deficiency

3-Methylglutaconic Aciduria Type 1

Mga1

MGCA1

3mg-Coa Hydratase Deficiency

Mga Type I

Mga, Type I

3-Mg-Coa-Hydratase Deficiency

3 Methylglutaconyl Coa Hydratase Deficiency

3-Methylglutaconic Aciduria Type I

3 Alpha Methylglutaconic Aciduria Type I

3 Methylglutaconic Aciduria Type 1

3-Mgca Type I

3mg Coa Hydratase Deficiency

Auh Defect

Primary 3-Methylglutaconic Aciduria

3-Methylglutaconic Aciduria 1

3-Alpha-Methylglutaconic Aciduria Type 1

3-Alpha-Methylglutaconyl-Coa Hydratase Deficiency

3-@Methylglutaconic Aciduria, Type I

Megaloblastic Anemia Due To Inborn Errors Of Metabolism
Muscular Atrophy

Muscle Wasting

Amyotrophia

Wasting - Muscle

Skeletal Muscle Atrophy
Aceruloplasminemia

Cerebellar Ataxia

Hypoceruloplasminemia

Hemosiderosis, Systemic, Due To Aceruloplasminemia

Familial Apoceruloplasmin Deficiency

Hereditary Ceruloplasmin Deficiency

Deficiency Of Ferroxidase

Hypoceruloplasminemia, Hereditary

Ceruloplasmin Deficiency

Systemic Hemosiderosis Due To Aceruloplasminemia

ACERULOP
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07698 LIX1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS07699 LIX1L Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus LIX1 VGNC VGNC:102244
Canis familiaris LIX1 VGNC VGNC:42702
Mus musculus LIX1 MGD MGI:1913893
Bos taurus LIX1 VGNC VGNC:30912
Macaca mulatta LIX1 VGNC VGNC:74311
Rattus norvegicus LIX1 RGD RGD:1309454
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