2. Gene
  3. Pde1c - phosphodiesterase 1C Gene

Pde1c - phosphodiesterase 1C Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 18575 | 基因类型: protein coding

关于 Pde1c

功能概要

Predicted to enable cAMP binding activity; calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity; and calmodulin-dependent cyclic-nucleotide phosphodiesterase activity. Acts upstream of or within sensory perception of smell. Located in cilium. Is expressed in several structures, including alimentary system; integumental system; male reproductive gland or organ; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 74. Orthologous to human PDE1C (phosphodiesterase 1C). [provided by Alliance of Genome Resources, Apr 2022]

Pde1c 基因产物(15)

mRNA Protein Name
NM_001025568.3 NP_001020739.1 dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform b
NM_001159952.2 NP_001153424.1 dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform c
NM_001159953.2 NP_001153425.1 dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform d
NM_001159955.2 NP_001153427.1 dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform a
NM_001159956.2 NP_001153428.1 dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform f
NM_001159957.2 NP_001153429.1 dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform e
NM_001159960.2 NP_001153432.1 dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform b
NM_001355475.2 NP_001342404.1 dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform a
NM_001410253.1 NP_001397182.1 dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform b
NM_001410254.1 NP_001397183.1 dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform b
NM_001410255.1 NP_001397184.1 dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform g
NM_001410256.1 NP_001397185.1 dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform h
NM_001410257.1 NP_001397186.1 dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform i
NM_001410258.1 NP_001397187.1 dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform j
NM_011054.5 NP_035184.1 dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 3',5'-cyclic-AMP phosphodiesterase activity IDA
IDA: 通过直接分析推断
8810348 MGI
enables 3',5'-cyclic-GMP phosphodiesterase activity IDA
IDA: 通过直接分析推断
8810348 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within sensory perception of smell IGI
IGI: 通过遗传相互作用推断
19305400 MGI
acts upstream of or within sensory perception of smell IMP
IMP: 通过突变表型推断
19305400 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cilium IDA
IDA: 通过直接分析推断
19305400 MGI
located in lysosome IDA
IDA: 通过直接分析推断
29860631 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C

calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C

3',5'-cyclic-AMP phosphodiesterase

3',5'-cyclic-GMP phosphodiesterase

cam-PDE 1C

dual specificity Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C

相关产品

Clinical Phase
生物活性分子 (3)
目录号 产品名 作用方式
纯度 Phase
HY-12501A ITI-214 Inhibitor 99.19% Phase 2
HY-112831 Osoresnontrine Inhibitor 99.88% Phase 2
HY-12501 ITI-214 free base Inhibitor 98.0% Phase 2
Pre-clinical Phase
生物活性分子 (12)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-101490 PDE1-IN-2 Inhibitor 98.0% 否
HY-169402 PDE1-IN-9 Inhibitor / 否
HY-169402A PDE1-IN-9 hydrochloride Inhibitor / 否
HY-120741 PF-04822163 Inhibitor / 否
HY-120195 PF-04677490 Inhibitor / 否
HY-120195A PF-04827736 Inhibitor / 否
HY-147946 PDE1-IN-4 Inhibitor / 否
HY-155199 PDE1-IN-5 Inhibitor / 否
HY-RS10212 PDE1C Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19228 Pde1c Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25717 Pde1c Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-U00374 Sch59498 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pde1c NCBI NCBI:5137
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