2. Gene
  3. Mapk8ip1 - mitogen-activated protein kinase 8 interacting protein 1 Gene

Mapk8ip1 - mitogen-activated protein kinase 8 interacting protein 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: IB1; Jip1; Skip; JIP-1; Prkm8ip; mjip-2a

基因 ID: 19099 | 基因类型: protein coding

关于 Mapk8ip1

功能概要

Enables Kinesin binding activity and protein kinase binding activity. Involved in positive regulation of JNK cascade and regulation of CD8-positive, alpha-beta T cell proliferation. Acts upstream of or within several processes, including JUN phosphorylation; negative regulation of intrinsic apoptotic signaling pathway; and regulation of transcription, DNA-templated. Located in several cellular components, including cell body; dendrite; and dentate gyrus mossy fiber. Is expressed in intestine smooth muscle circular layer; nervous system; renal vasculature; and sensory organ. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human MAPK8IP1 (mitogen-activated protein kinase 8 interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Mapk8ip1 基因产物(3)

mRNA Protein Name
NM_001202445.1 NP_001189374.1 C-Jun-amino-terminal kinase-interacting protein 1 isoform 2
NM_001202446.1 NP_001189375.1 C-Jun-amino-terminal kinase-interacting protein 1 isoform 3
NM_011162.5 NP_035292.2 C-Jun-amino-terminal kinase-interacting protein 1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables kinesin binding IPI
IPI: 通过物理相互作用推断
11238452 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
10827173 MGI
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
11562351 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within JUN phosphorylation IDA
IDA: 通过直接分析推断
9235893 MGI
acts upstream of or within negative regulation of intrinsic apoptotic signaling pathway IDA
IDA: 通过直接分析推断
10098834 MGI
involved in positive regulation of JNK cascade IMP
IMP: 通过突变表型推断
23963642 MGI
involved in regulation of CD8-positive, alpha-beta T cell proliferation IMP
IMP: 通过突变表型推断
23963642 MGI
acts upstream of or within regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
9235893 MGI
involved in regulation of JNK cascade IMP
IMP: 通过突变表型推断
11562351 MGI
acts upstream of or within signal transduction IDA
IDA: 通过直接分析推断
9235893 MGI
acts upstream of or within vesicle-mediated transport IDA
IDA: 通过直接分析推断
16301330 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
10712642 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
10712642 MGI
located in cytosol IDA
IDA: 通过直接分析推断
10712642 MGI
located in dendrite IDA
IDA: 通过直接分析推断
10712642 MGI
located in dentate gyrus mossy fiber IDA
IDA: 通过直接分析推断
10712642 MGI
located in membrane IDA
IDA: 通过直接分析推断
10712642 MGI
located in neuron projection IDA
IDA: 通过直接分析推断
16301330 MGI
located in neuronal cell body IDA
IDA: 通过直接分析推断
10712642 MGI
located in synapse IDA
IDA: 通过直接分析推断
10712642 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

C-Jun-amino-terminal kinase-interacting protein 1

IB-1

JNK MAP kinase scaffold protein 1

JNK-interacting protein 1

islet-brain-1

protein kinase, mitogen-activated 8 interacting protein

Mapk8ip1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Mapk8ip1 Q9WVI9 Lrp1 Mus musculus Q91ZX7
Pull Down
10827173
种属内
Mapk8ip1 Q9WVI9 Lrp1 Mus musculus Q91ZX7
Y2H
10827173
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08124 MAPK8IP1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22065 Mapk8ip1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mapk8ip1 NCBI NCBI:9479
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z