2. Gene
  3. Dusp1 - dual specificity phosphatase 1 Gene

Dusp1 - dual specificity phosphatase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: erp; MKP1; mkp-1; 3CH134; Ptpn16

基因 ID: 19252 | 基因类型: protein coding

关于 Dusp1

功能概要

Enables mitogen-activated protein kinase binding activity and phosphoprotein Phosphatase activity. Involved in negative regulation of MAPK cascade; negative regulation of cell population proliferation; and protein dephosphorylation. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Human ortholog(s) of this gene implicated in breast Cancer. Orthologous to human DUSP1 (dual specificity Phosphatase 1). [provided by Alliance of Genome Resources, Apr 2022]

Dusp1 基因产物(1)

mRNA Protein Name
NM_013642.3 NP_038670.1 dual specificity protein phosphatase 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables MAP kinase tyrosine/serine/threonine phosphatase activity IMP
IMP: 通过突变表型推断
8221888 MGI
enables mitogen-activated protein kinase binding IDA
IDA: 通过直接分析推断
8221888 MGI
enables mitogen-activated protein kinase binding IPI
IPI: 通过物理相互作用推断
8221888 MGI
enables protein serine/threonine phosphatase activity IMP
IMP: 通过突变表型推断
8355678 MGI
enables protein tyrosine phosphatase activity IMP
IMP: 通过突变表型推断
8355678 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of MAPK cascade IMP
IMP: 通过突变表型推断
8221888 MGI
involved in negative regulation of cell population proliferation IMP
IMP: 通过突变表型推断
8355678 MGI
involved in peptidyl-serine dephosphorylation IMP
IMP: 通过突变表型推断
8355678 MGI
involved in peptidyl-threonine dephosphorylation IMP
IMP: 通过突变表型推断
8221888 MGI
involved in peptidyl-tyrosine dephosphorylation IMP
IMP: 通过突变表型推断
8221888 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

dual specificity protein phosphatase 1

MAP kinase phosphatase 1

mitogen-activated protein kinase phosphatase-1

protein tyrosine phosphatase, non-receptor type 16

protein-tyrosine phosphatase 3CH134

protein-tyrosine phosphatase ERP

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-N2179 Hypaphorine Inhibitor 99.97% 否
HY-N15122 Aurovertin B / 否
HY-RS04050 DUSP1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS04053 DUSP12 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16828 Dusp1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23270 Dusp1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dusp1 NCBI NCBI:1843
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