2. Gene
  3. Trim72 - tripartite motif-containing 72 Gene

Trim72 - tripartite motif-containing 72 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: MG53

基因 ID: 434246 | 基因类型: protein coding

关于 Trim72

功能概要

Enables phosphatidylserine binding activity; ubiquitin conjugating enzyme binding activity; and ubiquitin protein Ligase activity. Involved in several processes, including muscle organ development; plasma membrane repair; and protein homooligomerization. Acts upstream of or within negative regulation of myotube differentiation; negative regulation of signal transduction; and proteasome-mediated ubiquitin-dependent protein catabolic process. Located in cytoplasmic vesicle membrane and sarcolemma. Is expressed in heart; heart left ventricle; heart right ventricle; left atrium; and right atrium. Orthologous to human TRIM72 (tripartite motif containing 72). [provided by Alliance of Genome Resources, Apr 2022]

Trim72 基因产物(1)

mRNA Protein Name
NM_001079932.3 NP_001073401.1 tripartite motif-containing protein 72
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables phosphatidylserine binding IDA
IDA: 通过直接分析推断
19043407 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
19380584 MGI
enables ubiquitin conjugating enzyme binding IDA
IDA: 通过直接分析推断
23965929 MGI
enables ubiquitin protein ligase activity IMP
IMP: 通过突变表型推断
23965929 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in muscle organ development IMP
IMP: 通过突变表型推断
19043407 MGI
involved in muscle system process IMP
IMP: 通过突变表型推断
19043407 MGI
acts upstream of or within negative regulation of insulin receptor signaling pathway IDA
IDA: 通过直接分析推断
23965929 MGI
acts upstream of or within negative regulation of insulin-like growth factor receptor signaling pathway IGI
IGI: 通过遗传相互作用推断
23965929 MGI
acts upstream of or within negative regulation of myotube differentiation IDA
IDA: 通过直接分析推断
23965929 MGI
acts upstream of or within plasma membrane repair IMP
IMP: 通过突变表型推断
19380584 MGI
involved in plasma membrane repair IMP
IMP: 通过突变表型推断
19043407 MGI
acts upstream of or within proteasome-mediated ubiquitin-dependent protein catabolic process IMP
IMP: 通过突变表型推断
23965929 MGI
involved in protein homooligomerization IPI
IPI: 通过物理相互作用推断
19043407 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasmic vesicle membrane IDA
IDA: 通过直接分析推断
19029292 MGI
located in sarcolemma IDA
IDA: 通过直接分析推断
19029292 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

tripartite motif-containing protein 72

mitsugumin 53

Trim72 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Trim72 Q1XH17 Irs1 Mus musculus P35569
Anti Bait CoIP
23354051
种属内
Trim72 Q1XH17 Irs1 Mus musculus P35569
Anti Tag CoIP
23354051
种属内
Trim72 Q1XH17 Insr Mus musculus P15208
Anti Bait CoIP
23354051
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15071 TRIM72 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21211 Trim72 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27727 Trim72 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Trim72 NCBI NCBI:493829
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