ALG10 - ALG10 alpha-1,2-glucosyltransferase Gene

中文名称：ALG10 α-1,2-葡萄糖基转移酶

种属: Homo sapiens

同用名: DIE2; KCR1; ALG10A

关于 ALG10

功能概要

该基因编码一种膜相关蛋白，该蛋白将第三个葡萄糖残基添加到脂质连接的寡糖前体以进行 N 连接糖基化。也就是说，它将末端葡萄糖从多萜醇磷酸葡萄糖 (Dol-P-Glc) 转移到脂质连接的寡糖 Glc2Man9GlcNAc (2) -PP-Dol 上。大鼠蛋白同系物显示出特异性调节大鼠神经元 ether-a-go-go (EAG) 钾离子通道的门控功能。[RefSeq 提供，2010 年 1 月]

This gene encodes a membrane-associated protein that adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. That is, it transfers the terminal glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc2Man9GlcNAc(2)-PP-Dol. The rat protein homolog was shown to specifically modulate the gating function of the rat neuronal ether-a-go-go (EAG) potassium ion channel. [provided by RefSeq, Jan 2010]