2. 疾病领域
  3. 炎症和免疫系统疾病 呼吸系统疾病
  4. 下呼吸道炎症 病原体感染引起的炎症 呼吸道炎症 慢性疾病与炎症
  5. 肺炎
  6. Hepoxilin A3

Hepoxilin A3 (HXA3) 是一种中性粒细胞趋化因子，通过激活 PLA2-12-LOX 通路合成。Hepoxilin A3 可引导中性粒细胞跨越上皮屏障迁移至感染部位 (如肺泡腔)。Hepoxilin A3 的水平在小鼠模型中与中性粒细胞浸润同步升高。Hepoxilin A3 可用于研究炎症疾病 (如肺炎、囊性纤维化)。

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Hepoxilin A3

Hepoxilin A3 Chemical Structure

CAS No. : 94161-11-2

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Hepoxilin A3 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Hepoxilin A3 (HXA3) is a neutrophil chemo-attractant, synthesized by activating the PLA2-12-LOX pathway. Hepoxilin A3 can guide neutrophils to cross the epithelial barrier and migrate to the infection site (such as the alveolar cavity). The level of Hepoxilin A3 increases synchronously with neutrophil infiltration in mouse models. Hepoxilin A3 can be used to study inflammatory diseases (such as pneumonia, cystic fibrosis)[1].

分子量

336.47

Formula

C20H32O4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Hepoxilin A3 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Hepoxilin A394161-11-2HXA3Hepoxilin A 3Hepoxilin A-3HXA 3HXA-3OthersNeutrophilsBacterialLipid MediatorsChemotaxisInflammationLungPseudomonas aeruginosaEpithelial MigrationEicosanoidsInhibitorinhibitorinhibit

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