Search Result

Results for "

Hamster Model

" in MCE Product Catalog:

By Targets:	Androgen Receptor (3) Bacterial (1) CTLA-4 (1) CXCR (1) Cytochrome P450 (1) Drug Derivative (1) MMP (1) SARS-CoV (2) TGF-β Receptor (1) TNF Receptor (1) Virus Protease (2) Wnt (1) β-catenin (1)
By Research Areas:	Cancer (4) Endocrinology (2) Infection (3) Inflammation/Immunology (5) Metabolic Disease (2)

抑制剂 & 激动剂

抗体抑制剂

没找到您心仪的产品？我们拥有更多针对信号通路的抑制剂、激动剂、调节剂

您还可以尝试以下方式，我们的专业人员为您服务

Cat. No.	Product Name	Target	Research Area	Chemical Structure

HY-P990107

Anti-Mouse/Human/Rat/Monkey/Hamster/Canine/Bovine TGF-β Antibody (1D11.16.8)	TGF-β Receptor	Cancer
Anti-Mouse/Human/Rat/Monkey/Hamster/Canine/Bovine TGF-β Antibody (1D11.16.8) 是一种 TGF-β IgG 抗体抑制剂。Anti-Mouse/Human/Rat/Monkey/Hamster/Canine/Bovine TGF-β Antibody (1D11.16.8) 可减轻单侧输尿管梗阻 (UUO) 模型小鼠的肾纤维化。Anti-Mouse/Human/Rat/Monkey/Hamster/Canine/Bovine TGF-β Antibody (1D11.16.8) 在多种肿瘤模型中显示出强大的抗肿瘤作用，如胰腺癌。

HY-15996

Seviteronel VT-464	Cytochrome P450 Androgen Receptor	Cancer
Seviteronel (VT-464) 是 CYP17 裂解酶抑制剂，对h-Lyase的 IC₅₀ 为 69 nM，也是一种雄激素受体 (AR) 拮抗剂。

HY-W209580

N-Nitrosobis(2-oxopropyl)amine	Others	Cancer
N-Nitrosobis (2-oxopropyl) amine 是一种亚硝胺化合物，是一种致癌物质。使用 N-Nitrosobis (2-oxopropyl) amine 处理叙利亚金黄仓鼠是一种化学诱导癌症模型的方法，可代表人类胰腺癌。

HY-160659

Androgen receptor antagonist 10	Androgen Receptor	Endocrinology
Androgen receptor antagonist 10 (compound 6h) 是一种雄激素受体 (androgen receptor) 拮抗剂。Androgen receptor antagonist 10 降低叙利亚金仓鼠模型中的蜡酯。

HY-129819

(Rac)-DNDI-8219	Bacterial	Infection
(Rac)-DNDI-8219是一种抗结核化合物，具有强效的抗利什曼病活性。 (Rac)-DNDI-8219在Leishmania donovani小鼠模型中展示了优越的功效。 (Rac)-DNDI-8219在Leishmania infantum仓鼠模型中表现出可喜的活性。 (Rac)-DNDI-8219的候选化合物R-6在同样的仓鼠模型中提供了卓越的口服疗效。

HY-160680

AR antagonist 6	Androgen Receptor	Endocrinology
AR antagonist 6 (compound 6i) 是一种二苯醚类雄激素受体 (AR) 拮抗剂，可结合 AR 的浓度为 120 nM。AR antagonist 6 对金叙利亚仓鼠的耳模型，表现出低毒性和体外活性。

HY-107013

CP-544439	MMP	Inflammation/Immunology
CP-544439 是一种具有口服活性的 MMP-13 抑制剂，IC₅₀ 为 0.75 nM。

HY-P991761

Anti-Mouse CXCL10 Antibody (1F11)	CXCR	Inflammation/Immunology
Anti-Mouse CXCL10 Antibody (1F11) 与促炎因子 CXCL10 反应，可用于中和 CXCL10 (体外和体内)，并可在多种炎症疾病模型中抑制体内 T 细胞募集。Recommend Isotype Controls: Polyclonal Armenian hamster IgG, Isotype Control (HY-P990305).

HY-170309

NZ-804	SARS-CoV Virus Protease	Infection
NZ-804 是口服有效的 SARS-CoV-2 主要蛋白酶 Mpro 抑制剂，IC₅₀ 为 8.9 nM。NZ-804 可抑制 HeLa-hACE2 细胞中的 SARS-CoV-2 复制，EC₅₀ 为 14 nM。NZ-804 对多种 CoV 表现出广谱抗病毒活性。NZ-804 可在小鼠和仓鼠模型中减少病毒复制。

HY-168924

Wnt/β-catenin activator 1	Wnt β-catenin	Metabolic Disease
Wnt/β-catenin activator 1 (Compound 5m) 是口服有效的 Wnt/β-catenin 信号通路激活剂，可在 G1 期阻滞细胞周期，抑制脂肪细胞的早期增殖，并在细胞 3T3-L1 中抑制脂肪生成，IC₅₀ 为 330 nM。Wnt/β-catenin activator 1 在高脂饮食喂养的叙利亚金黄仓鼠模型中表现出抗脂肪生成和抗血脂异常活性。

HY-P990789

Anti-Mouse CTLA-4 Antibody (9H10)	CTLA-4	Others Inflammation/Immunology Cancer
Anti-Mouse CTLA-4 Antibody (9H10) 是一种叙利亚仓鼠 IgG 抗体抑制剂，靶向 CTLA-4。Anti-Mouse CTLA-4 Antibody (9H10) 可结合小鼠 CTLA-4，并阻断 CTLA-4 与其配体之间的相互作用。Anti-Mouse CTLA-4 Antibody (9H10) 在多种肿瘤模型中显示出强大的抗肿瘤作用，如乳腺癌和结肠癌。

HY-175029

ALG-097558	SARS-CoV Virus Protease	Infection
ALG-097558 是一种具有口服活性的 3CL 蛋白酶抑制剂。ALG-097558 对多种 SARS-CoV-2 变体以及其他人类冠状病毒 (如 SARS-CoV-1、α-HCoV 229E 和 β-HCoV OC43) 表现出泛冠状病毒活性。ALG-097558 表现出强大的抑制活性，对 SARS-CoV-2 3CL 蛋白酶的 IC₅₀ 为 2 nM，对 229E 3CL 蛋白酶的 IC₅₀ 为 6 nM。ALG-097558 在 SARS-CoV-2 仓鼠感染模型中显示出抗病毒活性。ALG-097558 可用于病毒感染的研究。

HY-106074

Mexiprostil MDL 646	Drug Derivative	Inflammation/Immunology
Mexiprostil (MDL 646) 是一种口服有效的胃保护剂，是一种合成的 Prostaglandin E1 (HY-B0131) 的类似物。Mexiprostil 在大鼠、狗和猫中对 Histamine (HY-B1204) 和 Bethanechol (HY-B0406) 引起的胃酸分泌有显著的抑制作用。Mexiprostil 在猫中还能抑制 Pentagastrin (HY-A0261) 引起的胃酸分泌增多，在狗和大鼠中则不能。Mexiprostil 未引起妊娠终止。Mexiprostil 可用于研究胃溃疡。

HY-P99148

Anti-Mouse/Rat/Rabbit TNF alpha Antibody (TN3-19.12)	TNF Receptor	Metabolic Disease Inflammation/Immunology
Anti-Mouse TNF alpha Antibody (TN3-19.12) 是一种源自亚美尼亚仓鼠宿主的抗小鼠 TNF alpha 的 IgG 抗体抑制剂。Anti-Mouse TNF alpha Antibody (TN3-19.12) 可中和上清液中从 LNC-8 细胞获得的细胞毒性。Anti-Mouse TNF alpha Antibody (TN3-19.12) 可减轻 LNC-8 细胞异种移植小鼠模型中实验性自身免疫性脑脊髓炎 (EAE) 的症状和严重程度。Anti-Mouse TNF alpha Antibody (TN3-19.12) 可预防非肥胖糖尿病 (NOD) 小鼠发生糖尿病。Anti-Mouse TNF alpha Antibody (TN3-19.12) 在 CD2F1 小鼠中显示出明显的放射增敏作用。

Cat. No.	Product Name	Target	Research Area	图片

HY-P990107

Anti-Mouse/Human/Rat/Monkey/Hamster/Canine/Bovine TGF-β Antibody (1D11.16.8)	TGF-β Receptor	Cancer
Anti-Mouse/Human/Rat/Monkey/Hamster/Canine/Bovine TGF-β Antibody (1D11.16.8) 是一种 TGF-β IgG 抗体抑制剂。Anti-Mouse/Human/Rat/Monkey/Hamster/Canine/Bovine TGF-β Antibody (1D11.16.8) 可减轻单侧输尿管梗阻 (UUO) 模型小鼠的肾纤维化。Anti-Mouse/Human/Rat/Monkey/Hamster/Canine/Bovine TGF-β Antibody (1D11.16.8) 在多种肿瘤模型中显示出强大的抗肿瘤作用，如胰腺癌。

HY-P990789

Anti-Mouse CTLA-4 Antibody (9H10)	CTLA-4	Others Inflammation/Immunology Cancer
Anti-Mouse CTLA-4 Antibody (9H10) 是一种叙利亚仓鼠 IgG 抗体抑制剂，靶向 CTLA-4。Anti-Mouse CTLA-4 Antibody (9H10) 可结合小鼠 CTLA-4，并阻断 CTLA-4 与其配体之间的相互作用。Anti-Mouse CTLA-4 Antibody (9H10) 在多种肿瘤模型中显示出强大的抗肿瘤作用，如乳腺癌和结肠癌。

HY-P99148

Anti-Mouse/Rat/Rabbit TNF alpha Antibody (TN3-19.12)	TNF Receptor	Metabolic Disease Inflammation/Immunology
Anti-Mouse TNF alpha Antibody (TN3-19.12) 是一种源自亚美尼亚仓鼠宿主的抗小鼠 TNF alpha 的 IgG 抗体抑制剂。Anti-Mouse TNF alpha Antibody (TN3-19.12) 可中和上清液中从 LNC-8 细胞获得的细胞毒性。Anti-Mouse TNF alpha Antibody (TN3-19.12) 可减轻 LNC-8 细胞异种移植小鼠模型中实验性自身免疫性脑脊髓炎 (EAE) 的症状和严重程度。Anti-Mouse TNF alpha Antibody (TN3-19.12) 可预防非肥胖糖尿病 (NOD) 小鼠发生糖尿病。Anti-Mouse TNF alpha Antibody (TN3-19.12) 在 CD2F1 小鼠中显示出明显的放射增敏作用。

HY-P991761

Anti-Mouse CXCL10 Antibody (1F11)	CXCR	Inflammation/Immunology
Anti-Mouse CXCL10 Antibody (1F11) 与促炎因子 CXCL10 反应，可用于中和 CXCL10 (体外和体内)，并可在多种炎症疾病模型中抑制体内 T 细胞募集。Recommend Isotype Controls: Polyclonal Armenian hamster IgG, Isotype Control (HY-P990305).

Your information is safe with us. * Required Fields.

* 客户姓名：			* 公司或机构名称：
* Email：			* 联系电话：
* 产品名称：			* 需求量：
目录号：			CAS号：
留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
目录号：
需求量：

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。	站点地图隐私声明
粤ICP备2021105330号-3 上海工商沪公网安备31011502019417 沪(浦)应急管危经许[2021]201709(QFYS) 营业执照（三证合一）
Copyright © 2013-2026 MedChemExpress. All Rights Reserved.

姓名
邮箱 *

Sorry, but the email address you supplied was invalid.

Hamster Model

抑制剂 & 激动剂

抗体抑制剂

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z