1. Protein Tyrosine Kinase/RTK
  2. FAK
  3. STARD3-IN-1

STARD3-IN-1 (Compound VS1) 是一种 STARD3 抑制剂,其 IC₅₀ 为 35 μM。STARD3是一种在多种癌症中过度表达并参与胆固醇运输的蛋白。STARD3-IN-1 在乳腺癌和结肠癌细胞中具有抗增殖活性,显著削弱癌细胞的克隆形成能力。STARD3-IN-1 升高了 FAK 和 pTyr397-FAK 的蛋白水平。STARD3-IN-1 可用于研究乳腺癌和结肠癌。

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STARD3-IN-1

STARD3-IN-1 Chemical Structure

CAS No. : 1424357-72-1

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

STARD3-IN-1 (Compound VS1) is a STARD3 inhibitor with an IC₅₀ of 35 μM. STARD3 is a protein that is overexpressed in various cancers and is involved in cholesterol transport. STARD3-IN-1 exhibits anti-proliferative activity in breast cancer and colon cancer cells, significantly weakening the clonogenic ability of cancer cells. STARD3-IN-1 increases the protein levels of FAK and pTyr397-FAK. STARD3-IN-1 can be used for research on breast cancer and colon cancer[1].

分子量

404.42

Formula

C22H20N4O4

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
STARD3-IN-1
目录号:
HY-W783415
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