2. Anti-infection
  3. Bacterial HIV Fungal
  4. Tachyplesin II

Tachyplesin II 是一种广谱的阳离子抗菌肽。Tachyplesin II 对革兰氏阳性菌、革兰氏阴性菌和部分真菌均有显著的抑制效果。Tachyplesin II 通过正电荷与细菌膜脂多糖结合，破坏膜完整性，导致细胞内容物泄漏。Tachyplesin II 可结合 DNA 小沟，抑制微生物复制，还能抑制 HIV-1 复制和肝癌细胞增殖。

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Custom Peptide Synthesis

Tachyplesin II

Tachyplesin II Chemical Structure

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Tachyplesin II 相关抗体

Top Publications Citing Use of Products

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HIV HIV-1 HIV-2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Tachyplesin II is a broad-spectrum cationic antimicrobial peptide. Tachyplesin II has significant inhibitory effects on Gram-positive bacteria, Gram-negative bacteria, and some fungi. Tachyplesin II binds to bacterial membrane lipopolysaccharides through its positive charge, disrupting membrane integrity and causing leakage of cellular contents. Tachyplesin II can bind to DNA grooves, inhibiting microbial replication, and also suppressing HIV-1 replication and the proliferation of liver cancer cells[1].

分子量

2264.73

Formula

C99H150N34O20S4
Sequence

Arg-Trp-Cys-Phe-Arg-Val-Cys-Tyr-Arg-Gly-Ile-Cys-Tyr-Arg-Lys-Cys-Arg (Disulfide bridge:Cys3-Cys16,Cys7-Cys12)
Sequence Shortening

RWCFRVCYRGICYRKCR (Disulfide bridge:Cys3-Cys16,Cys7-Cys12)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Tachyplesin II 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tachyplesin IIBacterialHIVFungalHuman immunodeficiency virusAntimicrobial peptidePichia pastorisHeterologous expressionDisulfide bondC-terminal amidationAntimicrobial spectrumMinimum inhibitory concentrationSize-exclusion chromatographyYeast codon optimizationInhibitorinhibitorinhibit

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目录号：
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