2. Cell Cycle/DNA Damage
  3. DNA/RNA Synthesis
  4. Tauromustine

Tauromustine 是一种口服有效的亚硝基脲类抗癌剂。Tauromustine 具有烷化作用，能够破坏 DNA 功能。Tauromustine 具有很高的治疗指数，尤其是对 Walker 256 大鼠癌肉瘤的治疗，对黑色素瘤、乳腺癌、胸膜间皮瘤和卵巢癌也有活性。Tauromustine 主要在肝脏代谢，但部分代谢物本身也具有细胞毒性。

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Tauromustine

Tauromustine Chemical Structure

CAS No. : 85977-49-7

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Tauromustine 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Tauromustine is an orally active nitrosourea anticancer agent. Tauromustine has an alkylation effect and can damage the DNA function. Tauromustine has a high therapeutic index, especially in the treatment of Walker 256 rat sarcoma. It is also active against melanoma, breast cancer, pleural mesothelioma and ovarian cancer. Tauromustine is mainly metabolized in the liver, but some of its metabolites also have cytotoxicity[1][2][3].

分子量

286.74

Formula

C7H15ClN4O4S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Tauromustine 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tauromustine85977-49-7DNA/RNA Synthesisnitrosoureacolorectal cancermalignant gliomaphase III trialquality of lifeSpitzer indexthrombocytopeniaInhibitorinhibitorinhibit

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