2. Metabolic Enzyme/Protease
  3. PAI-1 Ser/Thr Protease
  4. Upamostat hydrogen sulfate

Upamostat hydrogen sulfate  (Synonyms: WX-671 hydrogen sulfate)

目录号: HY-16512
产品使用指南 技术支持

Upamostat (WX-671) hydrogen sulfate，WX-UK1 的前药，是一种口服有效的丝氨酸蛋白酶 (serine protease) 抑制剂。Upamostat hydrogen sulfate 通过抑制尿激酶型纤溶酶原激活物 (uPA) 系统，阻断其介导的纤溶酶原激活过程，从而抑制肿瘤细胞的侵袭、迁移和转移。Upamostat hydrogen sulfate 可用于研究转移性乳腺癌和局部晚期胰腺癌。

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Upamostat hydrogen sulfate

Upamostat hydrogen sulfate Chemical Structure

CAS No. : 798560-68-6

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Upamostat hydrogen sulfate 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

生物活性

Upamostat (WX-671) hydrogen sulfate, a prodrug of WX-UK1, is an orally active serine protease inhibitor. Upamostat hydrogen sulfate inhibits the urokinase-type plasminogen activator (uPA) system, blocking the plasminogen activation process mediated by it, thereby suppressing the invasion, migration and metastasis of tumor cells. Upamostat hydrogen sulfate can be used in the research of metastatic breast cancer and locally advanced pancreatic cancer[1].

分子量

1357.70

Formula

C64H96N10O16S3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Upamostat hydrogen sulfate 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Upamostat hydrogen798560-68-6WX-671 hydrogenPAI-1Ser/Thr ProteasePlasminogen activator inhibitor-1Serine proteasesSerine endopeptidasesThreonine proteasesuPA inhibitoramidoxime prodrugmARC enzyme systempharmacokineticspancreatic cancergemcitabine combination therapyInhibitorinhibitorinhibit

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