2. PROTAC Cell Cycle/DNA Damage
  3. PROTACs Microphthalmia Associated Transcription Factor (MITF)
  4. WZS0347

WZS0347 是一种 MITF PROTAC 降解剂。WZS0347 有效地降低了几种黑色素瘤细胞系的 MITF 蛋白水平，包括 B16F10、A375 和 GAK。WZS0347 显著抑制黑色素瘤细胞的增殖、迁移和侵袭。WZS0347 可用于研究黑色素瘤 (Pink: MITF 配体: (HY-179718); Blue: CRBN 配体: (HY-131717); Black: 连接子 : (HY-22391))。

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WZS0347

WZS0347 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
5 mg ￥6760
6 - 8 周
10 mg 询价 6 - 8 周
25 mg 询价 6 - 8 周
50 mg 询价 6 - 8 周
100 mg   询价  
200 mg   询价  

* Please select Quantity before adding items.

Customer Review

WZS0347 相关抗体

Top Publications Citing Use of Products

查看 PROTACs 亚型特异性产品:

查看所有亚型
von Hippel-Lindau (VHL) Cereblon MDM2 cIAP1

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

WZS0347 is a MITF PROTAC degrader. WZS0347 effectively reduces the MITF protein levels in several melanoma cell lines, including B16F10, A375, and GAK. WZS0347 significantly inhibits the proliferation, migration, and invasion of melanoma cells. WZS0347 can be used for research on melanoma (Pink: MITF ligand: (HY-179718); Blue: CRBN ligand: (HY-131717); Black: linker: (HY-22391))[1].

IC50 & Target[1]

Cereblon

 

分子量

790.82

Formula

C41H42N8O9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

WZS0347 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

WZS0347WZS 0347WZS-0347PROTACsMicrophthalmia Associated Transcription Factor (MITF)Microphthalmia Associated Transcription FactorMITFTranscription factorProteolysis-targeting chimeraMelanomaChemical probeInhibitorinhibitorinhibit

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产品名称：
WZS0347
目录号：
HY-179717
需求量：

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