| 常用名 | 苯氧苄胺 | CAS号 | 63-92-3 |
|---|---|---|---|
| 价格 | ¥需询单/1g | 纯度 | 98.9% |
| 备货期 | 1天 | 库存 | 现货 |
| 产品详情(用途,包装等)
Phenoxybenzamine hydrochloride is an α-1 adrenergic receptor antagonist used to treat hypertension and as a peripheral vasodilator. Phenoxybenzamine reduced neuronal death in rat hippocampal slice cultures following exposure to oxygen glucose deprivation. Phenoxybenzamine treated TBI (traumatic brain injury) animals also showed a significant improvement in both learning and memory compared to saline treated controls. At 32 h post-TBI phenoxybenzamine treated animals had significantly lower expression of pro-inflammatory signaling proteins CCL2, IL1β, and MyD88, suggesting that phenoxybenzamine may exert a neuroprotective effect by reducing neuroinflammation after TBI. |