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26934-87-2

26934-87-2 structure
26934-87-2 structure
  • Name: ht-2 toxin
  • Chemical Name: ht-2 toxin
  • CAS Number: 26934-87-2
  • Molecular Formula: C22H32O8
  • Molecular Weight: 424.485
  • Catalog: analytical chemistry Standard Food and cosmetics standards
  • Create Date: 2018-02-10 08:00:00
  • Modify Date: 2025-08-27 21:04:52
  • HT-2 Toxin is an active, deacetylated metabolite of the T-2 toxin. HT-2 toxin inhibits protein synthesis and cell proliferation in plants[1][2].
Name ht-2 toxin
Synonyms HT-2
T-2,Toxin analog
Butanoic acid, 3-methyl-, (2α,3α,4β,6β,8β,11β,12α)-15-(acetyloxy)-12,13-epoxy-3,4-dihydroxytrichothec-9-en-8-yl ester
valerate
Toxin HT 2
(3β,4α,8α)-15-Acetoxy-3,4-dihydroxy-12,13-epoxytrichothec-9-en-8-yl 3-methylbutanoate
(3α,4β,8α)-15-(acetyloxy)-3,4-dihydroxy-12,13-epoxytrichothec-9-en-8-yl 3-methylbutanoate
Pentanoic acid anion
Trichothec-9-ene-3α,4β,8α,15-tetrol, 12,13-epoxy-, 15-acetate 8-isovalerate (8CI)
Mycotoxin HT 2
12,13-Epoxytrichothec-9-ene-3-α,4-β,8-α,15-tetrol 15-acetate 8-isovalerate
ht-2toxin solution
Description HT-2 Toxin is an active, deacetylated metabolite of the T-2 toxin. HT-2 toxin inhibits protein synthesis and cell proliferation in plants[1][2].
Related Catalog
References

[1]. Nathanail, A.V., et al. Metabolism of the fusarium mycotoxins T-2 toxin and HT-2 toxin in wheat J.Agric.Food Chem 63(35), 7862-7872 (2015).

[2]. Berthiller, F., et al. Masked mycotoxins: A review Mol.Nutr.Food Res. 57, 165-186 (2013).
Density 1.3±0.1 g/cm3
Boiling Point 537.1±50.0 °C at 760 mmHg
Molecular Formula C22H32O8
Molecular Weight 424.485
Flash Point 179.8±23.6 °C
Exact Mass 424.209717
PSA 114.82000
LogP 2.27
Vapour Pressure 0.0±3.2 mmHg at 25°C
Index of Refraction 1.562
Storage condition −20°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YD0050000
CHEMICAL NAME :
Trichothec-9-ene-3-alpha,4-beta,8-alpha,15-tetrol, 12,13-epoxy-, 15-acetate, 8-isovalerate
CAS REGISTRY NUMBER :
26934-87-2
LAST UPDATED :
199306
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C22-H32-O8
MOLECULAR WEIGHT :
424.54

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - guinea pig
REFERENCE :
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 4,S124,1984 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 26,923,1988
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intracerebral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
52 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - fluid intake Behavioral - ataxia
REFERENCE :
TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 26,923,1988
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3800 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 6,191,1981
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
6500 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ABCHA6 Agricultural and Biological Chemistry. (Maruzen Co. Ltd., POB 5050, Tokyo International, Tokyo 100-31, Japan) V.25- 1961- Volume(issue)/page/year: 46,2613,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
6700 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 24,985,1986
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
500 ug/kg
TOXIC EFFECTS :
Blood - hemorrhage
REFERENCE :
DFSCDX Developments in Food Science. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1978- Volume(issue)/page/year: 4,135,1983
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - chicken
DOSE/DURATION :
7220 ug/kg
TOXIC EFFECTS :
Gastrointestinal - hypermotility, diarrhea Behavioral - muscle weakness Behavioral - food intake (animal)
REFERENCE :
AEMIDF Applied and Environmental Microbiology. (American Soc. for Microbiology, 1913 I St., NW, Washington, DC 20006) V.31- 1976- Volume(issue)/page/year: 35,636,1978
Hazard Codes T+,T,Xn,F
Risk Phrases 26/27/28-36/37/38-36-20/21/22-11
Safety Phrases 22-26-36/37/39-45-36/37-16
RIDADR UN 3462 6.1/PG 1
WGK Germany 3
RTECS YD0050000
Packaging Group I
Hazard Class 6.1(a)
Precursor  3

DownStream  0

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