N,N,N',N'-TETRAMETHYLBENZIDINE

Modify Date: 2025-08-21 19:57:19

N,N,N',N'-TETRAMETHYLBENZIDINE structure	Common Name	N,N,N',N'-TETRAMETHYLBENZIDINE
	CAS Number	366-29-0	Molecular Weight	240.34300
	Density	1.041g/cm3	Boiling Point	387.1ºC at 760 mmHg
	Molecular Formula	C₁₆H₂₀N₂	Melting Point	193-195 °C(lit.)
	MSDS	Chinese USA	Flash Point	173.4ºC
	Symbol	GHS07	Signal Word	Warning

Name	n,n,n',n'-tetramethylbenzidine
Synonym	More Synonyms

Density	1.041g/cm3
Boiling Point	387.1ºC at 760 mmHg
Melting Point	193-195 °C(lit.)
Molecular Formula	C₁₆H₂₀N₂
Molecular Weight	240.34300
Flash Point	173.4ºC
Exact Mass	240.16300
PSA	6.48000
LogP	3.48560
Index of Refraction	1.605
InChIKey	YRNWIFYIFSBPAU-UHFFFAOYSA-N
SMILES	CN(C)c1ccc(-c2ccc(N(C)C)cc2)cc1
Stability	Stable. Incompatible with acids, acid chlorides, acid anhydrides, oxidizing agents.

N,N,N',N'-TETRAMETHYLBENZIDINE MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DD1752100

CHEMICAL NAME :: Benzidine, N,N,N',N'-tetramethyl-

CAS REGISTRY NUMBER :: 366-29-0

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C16-H20-N2

MOLECULAR WEIGHT :: 240.38

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 10 nmol/plate

REFERENCE :: EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 10,263,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X8275 No. of Facilities: 10 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 21 (estimated) No. of Female Employees: 21 (estimated)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi,Xn
Risk Phrases	R36/37/38:Irritating to eyes, respiratory system and skin . R40:Limited evidence of a carcinogenic effect. R22:Harmful if swallowed.
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	DD1752100
HS Code	2921590090

Precursor 10
CAS#:586-77-6 4-Bromo-N,N-dim... CAS#:28611-39-4 4-(Dimethylamin... CAS#:7353-91-5 4-(\|N\|,\|N\|-Dime... CAS#:22525-90-2 4-(dimethylamin...
CAS#:121-69-7 N,N-Dimethylaniline CAS#:698-70-4 4-Iodo-N,N-dime... CAS#:59130-74-4 4-[4-(dimethyla... CAS#:2996-92-1 Phenyltrimethox...
CAS#:106-49-0 p-Toluidine CAS#:108-91-8 Cyclohexylamine
DownStream 1
CAS#:366-29-0 N,N,N',N'-TETRA...

HS Code	2921590090
Summary	2921590090. other aromatic polyamines and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Loss of Endocan tumorigenic properties after alternative splicing of exon 2.

BMC Cancer 8 , 14, (2008)

Endocan was originally described as a dermatan sulfate proteoglycan found freely circulating in the blood. Endocan expression confers tumorigenic properties to epithelial cell lines or accelerate the ...

A triple-labeling method: HRP anterograde tract tracing combined with double immunofluorescent cell staining in developing neural tissue of the rat.

J. Neurosci. Methods 30 , 71, (1989)

In this paper we describe a triple-labeling technique on a single section of developing nervous tissue. This labelling consists of a histochemical visualization of anterogradely transported horseradis...

Glutathione conjugate formation without N-demethylation during the peroxidase catalysed N-oxidation of N,N',N,N'-tetramethylbenzidine.

Chem. Biol. Interact. 61(1) , 61-74, (1987)

The mechanism of peroxidative N-dealkylation of alkylamines proceeds via one-electron oxidation to the iminium cation which reacts with water to give the N-hydroxymethyl derivative which decomposes to...

Name: Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: HCMV UL50
External Id: HMS1262

Name: A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS979

Name: Cell-based high throughput primary assay to identify activators of GPR151
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id: GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

Name: qHTS assay for inhibitors of human lactate dehydrogenase
Source: NCGC
Target: N/A
External Id: LDHA

Name: Dicer-mediated maturation of pre-microRNA
Source: Center for Chemical Genomics, University of Michigan
Target: N/A
External Id: TargetID_659_CEMA

Name: NCI human tumor cell line growth inhibition assay. Data for the MCF7 Non-Small Cell L...
Source: DTP/NCI
Target: N/A
External Id: MCF7_OneDose

Name: Inhibitors of CDC25B-CDK2/CyclinA interaction
Source: Center for Chemical Genomics, University of Michigan
External Id: MScreen:TargetID_600

Name: NCI human tumor cell line growth inhibition assay. Data for the IGROV1 Non-Small Cell...
Source: DTP/NCI
Target: N/A
External Id: IGROV1_OneDose

Name: Primary qHTS Assay for Foot and Mouth Disease Virus Antivirals against NCGC Sytravon ...
Source: NCGC
External Id: stopgo-p2-SytraCBC-dual-FF

Name: High-throughput screen for inhibitors of the GIV GBA-motif interaction with Galpha-i ...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS1303

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4,4'-Bis(dimethylamino)biphenyl

N,N,N′,N′-Tetramethylbenzidine

N,N,N‘,N‘-Tetramethylbenzidine

4-[4-(dimethylamino)phenyl]-N,N-dimethylaniline

MFCD00008310

N,N,N',N'-Tetramethylbenzidine

EINECS 206-676-5

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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: N,N,N',N'-TETRAMETHYLBENZIDINE
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N,N,N',N'-TETRAMETHYLBENZIDINE

Names

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Safety Information

Synthetic Route

Precursor & DownStream

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Articles15

N,N,N',N'-TETRAMETHYLBENZIDINEBioassay

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@hg.y866.cn/chemical.