| Identification | More | [Name]
Benzyl 2-chloroacetate | [CAS]
140-18-1 | [Synonyms]
AKOS B029322
benzyl 2-chloroacetate
BENZYL-(CHLORACETAT)
BENZYL CHLOROACETATE
CHLOROACETIC ACID BENZYL ESTER
benzyl-alpha-chloroacetate
benzylmonochloracetate
chloro-aceticacibenzylester
chloro-aceticaciphenylmethylester
monochloroacetate
phenylmethylchloroacetate
2-CHLORO ACETIC ACID BENZYLESTER
Benzyl monochloroacetate
Acetic acid, chloro-, phenylmethyl ester
benzyl chloracetate
Phenylmethyl 2-chloroacetate | [EINECS(EC#)]
205-400-0 | [Molecular Formula]
C9H9ClO2 | [MDL Number]
MFCD00157062 | [Molecular Weight]
184.62 | [MOL File]
140-18-1.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [RTECS ]
AF8750000
| [HS Code ]
29154000 | [Toxicity]
LDLo ipr-mus: 500 mg/kg CBCCT* 8,99,56 |
| Hazard Information | Back Directory | [Chemical Properties]
Benzyl 2-chloroacetate is a colorless, slightly viscous liquid. Insoluble in water, soluble in alcohol and
oils. Sp.Gr = 1.22. Mild, Jasmin-type odor, floral-fruity, of
considerable tenacity. | [Uses]
Benzyl chloroacetate may be used:
- in the synthesis of monoesters of phosphonoacetic acid
- in the synthesis of N-benzoyl-glycyl- hydroxyl acetic acid, ester substrate for carboxypeptidase Y catalyzed peptide synthesis
- as reagent in the total syntheses of the (±)-di-O-methyl ethers of the norlignans sequirin-A, agatharesinol, and hinokiresinol, and of (±)-tri-O-methyl sequirin-E
| [Preparation]
From Benzyl alcohol and Monochloroacetic acid by direct esterification under azeotropic conditions. | [General Description]
Benzyl chloroacetate is an ester. | [Safety Profile]
Moderately toxic byintraperitoneal route. When heated todecomposition it emits toxic fumes of Cl- . |
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