| Identification | More | [Name]
Tanshinone I | [CAS]
568-73-0 | [Synonyms]
1,6,6-TRIMETHYL-6,7,8,9-TETRAHYDRO-PHENANTHRO[1,2-B]FURAN-10,11-DIONE
1,6-dimethyl-phenanthro[1,2-b]furan-10,11-dione
3,8,8-TRIMETHYL-8,9,10,11-TETRAHYDROPHENANTHRO[1,2-B]FURAN-1,2-DIONE
AKOS NCG1-0066
TANSHINONE I
TANSHINONE IIA
TANSHINONES IIA
TANSHINON I
Tanshinone
TANSHINONE I >98% BY HPLC FROM SALVIA MILTIORRHIZA B.
Phenanthro[1,2-b]furan-10,11-dione,1,6-dimethyl-
TanshinoneⅠ | [Molecular Formula]
C19H18O3 | [MDL Number]
MFCD00238692 | [Molecular Weight]
294.34 | [MOL File]
568-73-0.mol |
| Hazard Information | Back Directory | [Chemical Properties]
Purple to Brown powder | [Uses]
Tanshinone I is an extract from Danshen (Radix Salvia miltiorrhizae) and has been used for the treatment of cerebrovascular diseases such as ischemic stroke. | [Definition]
ChEBI: Tanshinone I is an abietane diterpenoid. It has a role as an anticoronaviral agent. | [Biological Activity]
Phenanthrenequinone constituent of Chinese medicinal herb Danshen (Salvia miltiorrhiza). Modulates or prevents breast cancer metastasis by regulating adhesion molecules. Anti-inflammatory.''TanshinoneI is extensively studied for its anticancer propertiesit was reported to inhibit cancer cell invasionmetastasisand migration and is a potent antitumor agent. It also displays antibacterialneuroprotectivememory-enhancingand cardioprotective activities. | [Cytotoxicity]
IC50 (μg/mL): 2.96 (A549), 2.14 (TOV-21G) (Chang et al. 2013)
IC50 (μg/mL): 10.5 (MIAPaCa-2) (Fronzaet al. 2011) |
|
|