Hecogenin
- CAS No.
- 467-55-0
- Chemical Name:
- Hecogenin
- Synonyms
- (25R);Hecoginin;HECOGENIN;Hocogenin;Hecogrnin;Hecogenin (>12-Oxotigogenin;Hecogenin (>80%);HECOGENIN 98.0% BY HPLC;5α-Spirostan-3β-ol-12-one
- CBNumber:
- CB0308063
- Molecular Formula:
- C27H42O4
- Molecular Weight:
- 430.62
- MDL Number:
- MFCD00067285
- MOL File:
- 467-55-0.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Hecogenin >80.0%(GC) | H0003 | 1g | $166 |
| Hecogenin >80.0%(GC) | H0003 | 100mg | $40 |
| Hecogenin ≥80% | 21372 | 100mg | $44 |
| Hecogenin ≥80% | 21372 | 250mg | $97 |
| Hecogenin ≥80% | 21372 | 1g | $193 |
| More product size | |||
| Melting point | 268°C |
|---|---|
| alpha | 7.2 º (c=0.8 g/100ml, CHCl3) |
| Boiling point | 464.85°C (rough estimate) |
| Density | 1.0040 (rough estimate) |
| refractive index | 1.4840 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 15.10±0.70(Predicted) |
| form | Solid |
| color | White to Off-White |
| Merck | 14,4622 |
| CAS DataBase Reference | 467-55-0(CAS DataBase Reference) |
| FDA UNII | 3XP44JJ79F |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |     GHS05,GHS06,GHS08,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H312-H315-H319-H371-H373-H317-H351-H335-H400-H290 | |||||||||
| Precautionary statements | P501-P273-P272-P260-P270-P202-P234-P201-P271-P264-P280-P390-P391-P337+P313-P305+P351+P338-P308+P311-P362+P364-P333+P313-P301+P310+P330-P302+P352+P312-P304+P340+P312-P403+P233-P406-P405 | |||||||||
| HS Code | 2937.29.9095 | |||||||||
| NFPA 704 |
|
Hecogenin price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | H0003 | Hecogenin >80.0%(GC) | 467-55-0 | 1g | $166 | 2025-07-31 | Buy |
| TCI Chemical | H0003 | Hecogenin >80.0%(GC) | 467-55-0 | 100mg | $40 | 2025-07-31 | Buy |
| Cayman Chemical | 21372 | Hecogenin ≥80% | 467-55-0 | 100mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 21372 | Hecogenin ≥80% | 467-55-0 | 250mg | $97 | 2024-03-01 | Buy |
| Cayman Chemical | 21372 | Hecogenin ≥80% | 467-55-0 | 1g | $193 | 2024-03-01 | Buy |
Hecogenin Chemical Properties,Uses,Production
Uses
antiinflammatory
Uses
Hecogenin, is a sapogenin present in the leaves of species from the Agave genus, possessing wide spectrum of pharmacology activities, such as having antinociceptive properties.
Definition
ChEBI: Hecogenin is a triterpenoid.
in vivo
Hecogenin (3.1-90 mg/kg; oral administration; for 15 hours; male Swiss mice) acutely administered, before ethanol, exhibits a potent gastroprotective effect. The Hecogenin pretreatment normalizes GSH levels and significantly reduces lipid peroxidation and nitrite levels in the stomach, as evaluated by the ethanol-induced gastric lesion model. Hecogenin also decreases MPO release and significantly protects the gastric mucosa[1].
| Animal Model: | Male Swiss mice (20-30 g) with ethanol[1] |
| Dosage: | 3.1 mg/kg, 7.5 mg/kg, 15 mg/kg, 30 mg/kg, 60 mg/kg and 90 mg/kg |
| Administration: | Oral administration; for 15 hours |
| Result: | Normalized GSH levels and significantly reduced lipid peroxidation and nitrite levels in the stomach, as evaluated by the ethanol-induced gastric lesion model. Decreased MPO release and significantly protected the gastric mucosa. |
Purification Methods
The saponin (~35 mg) in EtOAc is chromatographed on Al2O3 and eluted with *C6H6/Et2O, and the residue on evaporation is recrystallised from Me2CO. [Mazur et al. J Am Chem Soc 82 5889 1960, Marker et al. J Am Chem Soc 69 2167 1947, Beilstein 19 III/IV 2581.]
Hecogenin Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 +86-18192627656 | 1059@dideu.com | China | 3591 | 58 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29833 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 3751 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32470 | 58 |
| Longyan Tianhua Biological Technology Co., Ltd | 0086 18039857276 18039857276 | CHINA | 2783 | 58 | |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
View Lastest Price from Hecogenin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-01-05 | Hecogenin
467-55-0
|
US $60.00-89.00 / mg | 99.56% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-12-12 | Hecogenin
467-55-0
|
US $1.00-2.00 / KG | 1KG | 99% | 100000KG | Shaanxi Dideu Medichem Co. Ltd | |
 |
2023-02-24 | Hecogenin
467-55-0
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. |
