HECOGENIN ACETATE
- CAS No.
- 915-35-5
- Chemical Name:
- HECOGENIN ACETATE
- Synonyms
- HECOGENIN ACETATE;HECOGENIN ALCOHOL;HecogeninAcetate>(-)-HECOGENIN ACETATE, TECH., 90%;(25R)-3β-Acetoxy-5α-spirostane-12-one;Hecogenin acetate,()-Hecogenin acetate;(25R)-3β-Acetyloxy-5α-spirostan-12-one;(22R,25R)-3β-Acetoxy-5α-spirostane-12-one;12-oxo-5-alpha-spirostan-3-beta-yl acetate;(25R)-3β-Hydroxy-5α-spirostane-12-one=acetate
- CBNumber:
- CB6442059
- Molecular Formula:
- C29H44O5
- Molecular Weight:
- 472.66
- MDL Number:
- MFCD00005088
- MOL File:
- 915-35-5.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Hecogenin acetate ≥90% | H4274 | 25g | $664 |
| Hecogenin Acetate >90.0%(GC) | H0537 | 1g | $62 |
| Hecogenin Acetate >90.0%(GC) | H0537 | 5g | $160 |
| Hecogenin Acetate ≥98% | 25977 | 1g | $62 |
| Hecogenin Acetate ≥98% | 25977 | 5g | $166 |
| Melting point | 246-248 °C (dec.)(lit.) |
|---|---|
| Boiling point | 95-140 °C |
| Density | 1.15±0.1 g/cm3(Predicted) |
| refractive index | -4 ° (C=1, Dioxane) |
| storage temp. | Refrigerator |
| solubility | Chloroform (Sparingly), Dioxane (Sparingly, Heated), Ethyl Acetate (Slightly, Heated) |
| form | Solid |
| color | White |
| FDA UNII | 5K0WKD513R |
SAFETY
Risk and Safety Statements
| Safety Statements | 22-24/25 |
|---|---|
| WGK Germany | 3 |
| HS Code | 2937.29.9095 |
HECOGENIN ACETATE price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | H4274 | Hecogenin acetate ≥90% | 915-35-5 | 25g | $664 | 2023-01-07 | Buy |
| TCI Chemical | H0537 | Hecogenin Acetate >90.0%(GC) | 915-35-5 | 1g | $62 | 2025-07-31 | Buy |
| TCI Chemical | H0537 | Hecogenin Acetate >90.0%(GC) | 915-35-5 | 5g | $160 | 2025-07-31 | Buy |
| Cayman Chemical | 25977 | Hecogenin Acetate ≥98% | 915-35-5 | 1g | $62 | 2024-03-01 | Buy |
| Cayman Chemical | 25977 | Hecogenin Acetate ≥98% | 915-35-5 | 5g | $166 | 2024-03-01 | Buy |
HECOGENIN ACETATE Chemical Properties,Uses,Production
Description
Hecogenin acetate is a steroid sapogenin and an acetylated form of hecogenin that has anthelmintic and antinociceptive properties. It reduces the percentage of mobile larvae in goat fecal cultures containing Haemonchus, Oesophagostomum, and Trichostrongylus nematodes (EC50 = 0.49 mg/ml). Hecogenin acetate (5, 10, or 20 mg/kg, i.p.) inhibits development of mechanical hyperalgesia induced by carrageenan, TNF-α, dopamine , and prostaglandin E2 (PGE2; ) in mice. It also increases latency to tail withdrawal in the tail flick test and has no effect on motor performance in the rotarod test in mice when administered at a dose of 40 mg/kg.
Uses
Hecogenin Acetate, is a derivative of Hecogenin (H129945), which is a sapogenin present in the leaves of species from the Agave genus, possessing wide spectrum of pharmacology activities, such as having antinociceptive properties.
Definition
ChEBI: HECOGENIN ACETATE is a triterpenoid.
Purification Methods
Crystallise the acetate from MeOH. [Beilstein 19 IV 2583.]
References
[1] ACIDáLIA CARINE VIEIRA SANTOS. In vitro ovicidal and larvicidal activities of some saponins and flavonoids against parasitic nematodes of goats.[J]. Parasitology, 2018, 145 14: 1884-1889. DOI: 10.1017/s0031182018000689
[2] JULLYANA S S QUINTANS. Evidence for the involvement of spinal cord-inhibitory and cytokines-modulatory mechanisms in the anti-hyperalgesic effect of hecogenin acetate, a steroidal sapogenin-acetylated, in mice.[J]. Molecules, 2014, 19 6: 8303-8316. DOI: 10.3390/molecules19068303
[3] KELLY BARBOSA GAMA. Evidence for the Involvement of Descending Pain-Inhibitory Mechanisms in the Antinociceptive Effect of Hecogenin Acetate[J]. Journal of Natural Products , 2013, 76 4: 559-563. DOI: 10.1021/np3007342
HECOGENIN ACETATE Preparation Products And Raw materials
Raw materials
Preparation Products
HECOGENIN ACETATE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-17392712697 | 1022@dideu.com | China | 3995 | 58 |
| Aktin Chemicals, Inc. | 028-85159085 | info@aktinchem.com | CHINA | 1025 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43339 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| J & K SCIENTIFIC LTD. | 18210857532; 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40228 | 62 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24529 | 81 |
| Energy Chemical | 021-021-58432009 400-005-6266 | sales8178@energy-chemical.com | China | 44801 | 61 |
| Spectrum Chemical Manufacturing Corp. | 021-021-021-67601398-809-809-809 15221380277 | marketing_china@spectrumchemical.com | China | 9658 | 60 |
View Lastest Price from HECOGENIN ACETATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-08-25 | HECOGENIN ACETATE
915-35-5
|
US $0.00-0.00 / KG | 1KG | 99.0% | 1000KG | Shaanxi Dideu Medichem Co. Ltd |
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- HECOGENIN ACETATE
915-35-5
- US $0.00-0.00 / KG
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
