BML-259
- CAS No.
- 267654-00-2
- Chemical Name:
- BML-259
- Synonyms
- BML-259;CAY10554;BML-259, 10 mM in DMSO;N-(5-Isopropylthiazol-2-yl)-2-phenylacetamide;Benzeneacetamide, N-[5-(1-methylethyl)-2-thiazolyl]-;2-phenyl-N-(5-propan-2-yl-1,3-thiazol-2-yl)acetamide;BML-259,protein,p53,CDK,death,disease,neurotoxicity,cell,Inhibitor,inhibit,Cyclin dependent kinase,Alzheimer's
- CBNumber:
- CB12450947
- Molecular Formula:
- C14H16N2OS
- Molecular Weight:
- 260.35
- MDL Number:
- MFCD09802287
- MOL File:
- 267654-00-2.mol
| Product description | Number | Pack Size | Price |
| BML-259 recombinant | SRP0704 | 25mg | $352 |
| CAY10554 ≥95% | 10010301 | 5mg | $64 |
| CAY10554 ≥95% | 10010301 | 10mg | $119 |
| CAY10554 ≥95% | 10010301 | 25mg | $280 |
| CAY10554 ≥95% | 10010301 | 50mg | $497 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a |
| WGK Germany | WGK 3 |
| Storage Class | 11 - Combustible Solids |
BML-259 price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SRP0704 | BML-259 recombinant | 267654-00-2 | 25mg | $352 | 2025-07-31 | Buy |
| Cayman Chemical | 10010301 | CAY10554 ≥95% | 267654-00-2 | 5mg | $64 | 2024-03-01 | Buy |
| Cayman Chemical | 10010301 | CAY10554 ≥95% | 267654-00-2 | 10mg | $119 | 2024-03-01 | Buy |
| Cayman Chemical | 10010301 | CAY10554 ≥95% | 267654-00-2 | 25mg | $280 | 2024-03-01 | Buy |
| Cayman Chemical | 10010301 | CAY10554 ≥95% | 267654-00-2 | 50mg | $497 | 2024-03-01 | Buy |
BML-259 Chemical Properties,Uses,Production
Description
BML-259 (267654-00-2) is a potent inhibitor of Cdk5/p25 (IC50 = 64 nM) and Cdk2 (IC50 = 98nM).1
Uses
BML-259 is a potent cyclin-dependent kinase 5 (Cdk5) inhibitor, with IC50s of 64 and 98 nM for Cdk5 and Cdk2, respectively[1].
Definition
ChEBI: 2-phenyl-N-(5-propan-2-yl-2-thiazolyl)acetamide is a member of acetamides.
References
[1] CHRISTOPHER J. HELAL. Discovery and SAR of 2-aminothiazole inhibitors of cyclin-dependent kinase 5/p25 as a potential treatment for Alzheimer’s disease[J]. Bioorganic & Medicinal Chemistry Letters, 2004, 14 22: Pages 5521-5525. DOI:10.1016/j.bmcl.2004.09.006
BML-259 Preparation Products And Raw materials
Raw materials
Preparation Products
BML-259 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| NANJING YINGWEN BIOTECHNOLOGY CO LTD | +8613382787392 | sales@aeechem.com | China | 9999 | 58 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 12952 | 65 |
| Bide Pharmatech Ltd. | 400-400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9923 | 65 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71615 | 60 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6777 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11218 | 58 |
| Zhengzhou convergence chemical co., LTD | 037155153829 18003835034 | 3897192574@qq.com | China | 9993 | 58 |
