4-(cyanoMethylcarbaMoyl)phenylboronic acid
- CAS No.
- 1056636-11-3
- Chemical Name:
- 4-(cyanoMethylcarbaMoyl)phenylboronic acid
- Synonyms
- 4-(cyanoMethylcarbaMoyl)phenylboronic acid;4-(Carbonitrilmethylcarbamoyl)phenyl]boronic acid;B-[4-[[(Cyanomethyl)amino]carbonyl]phenyl]boronic acid;Boronicacid,B-[4-[[(cyanomethyl)amino]carbonyl]phenyl]-;(4-((Cyanomethyl)carbamoyl)phenyl)boronic acid（contains varying amounts of Anhydride）
- CBNumber:
- CB42657192
- Molecular Formula:
- C9H9BN2O3
- Molecular Weight:
- 203.99
- MDL Number:
- MOL File:
- 1056636-11-3.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| (4-((Cyanomethyl)carbamoyl)phenyl)boronicacid | 6087EA | 1g | $532 |
| (4-((Cyanomethyl)carbamoyl)phenyl)boronicacid 98% | A182842 | 25g | $954 |
| (4-((Cyanomethyl)carbamoyl)phenyl)boronicacid 95% | 6587233 | 100g | $1500 |
| (4-((Cyanomethyl)carbamoyl)phenyl)boronicacid 98% | A182842 | 100mg | $27 |
| (4-((Cyanomethyl)carbamoyl)phenyl)boronicacid 98% | A182842 | 250mg | $42 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Signal word | Warning |
|---|---|
| Hazard statements | H319-H315-H335-H302 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501 |
4-(cyanoMethylcarbaMoyl)phenylboronic acid price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AK Scientific | 6087EA | (4-((Cyanomethyl)carbamoyl)phenyl)boronicacid | 1056636-11-3 | 1g | $532 | 2021-12-16 | Buy |
| Ambeed | A182842 | (4-((Cyanomethyl)carbamoyl)phenyl)boronicacid 98% | 1056636-11-3 | 25g | $954 | 2021-12-16 | Buy |
| A1 Biochem Labs | 6587233 | (4-((Cyanomethyl)carbamoyl)phenyl)boronicacid 95% | 1056636-11-3 | 100g | $1500 | 2021-12-16 | Buy |
| Ambeed | A182842 | (4-((Cyanomethyl)carbamoyl)phenyl)boronicacid 98% | 1056636-11-3 | 100mg | $27 | 2021-12-16 | Buy |
| Ambeed | A182842 | (4-((Cyanomethyl)carbamoyl)phenyl)boronicacid 98% | 1056636-11-3 | 250mg | $42 | 2021-12-16 | Buy |
4-(cyanoMethylcarbaMoyl)phenylboronic acid Chemical Properties,Uses,Production
Synthesis
14047-29-1
6011-14-9
1056636-11-3
The general procedure for the synthesis of 4-cyanomethylcarbamoylphenylboronic acid from 4-carboxyphenylboronic acid and aminoacetonitrile hydrochloride was as follows: oxalyl chloride (5.9 mL, 66 mmol) was added dropwise to a suspension of 4-carboxyphenylboronic acid (5.0 g, 30 mmol) in DMF (5 mL) and dichloromethane (200 mL) at 0 °C. After the rate of gas release slowed down, the ice bath was removed and the reaction system was allowed to warm up to room temperature naturally within 30 min. Subsequently, the reaction mixture was heated at 40 °C for 3 h until all solids were completely dissolved. Dichloromethane was removed by distillation and the remaining DMF solution was cooled to 0 °C. At this temperature, a DMF (80 mL) solution of aminoacetonitrile hydrochloride (3.05 g, 33 mmol) and a solution of DIPEA (13 mL, 75 mmol) were slowly added dropwise. After completion of the dropwise addition, the ice bath was removed and the reaction mixture was stirred continuously for 16 hours at room temperature. Upon completion of the reaction, most of the DMF was evaporated under reduced pressure and the residue was subjected to liquid-liquid partitioning with ethyl acetate and 2 M aqueous hydrochloric acid. The aqueous phase was extracted twice more with ethyl acetate, and the organic phases were combined, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to afford 4-cyanomethylcarbamoylphenylboronic acid as a light yellow waxy solid (5.34 g, 87% yield). The product was characterized by 1HNMR (J6-DMSO, 300 MHz): δ 9.18 (1H, br, t, J=5.1 Hz), 7.8-7.9 (4H, m), 4.31 (2H, d, J=5.4 Hz).The LC-MS analysis showed the following results: retention time 0.9 min; mass-to-charge ratio m/z 203.3 [M-H]-.
References
[1] Patent: WO2009/29998, 2009, A1. Location in patent: Page/Page column 52-53
[2] Patent: WO2008/109943, 2008, A1. Location in patent: Page/Page column 60
4-(cyanoMethylcarbaMoyl)phenylboronic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 16513 | 58 |
| Shanghai Arbor Chemical Co., Ltd. | 021-60451682 | act@arborchemical.com | CHINA | 904 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| CD Chemical Group Limited | +8615986615575 | info@codchem.com | China | 17259 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53899 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39927 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
View Lastest Price from 4-(cyanoMethylcarbaMoyl)phenylboronic acid manufacturers
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2025-10-13 | {4-[(Cyanomethyl)carbamoyl]phenyl}boronic acid
1056636-11-3
|
US $3.00-9.00 / KG | 0.1KG | 99% | g-kg-tons, free sample is available | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
 |
2020-01-09 | 4-(cyanoMethylcarbaMoyl)phenylboronic acid
1056636-11-3
|
US $2.00 / KG | 1g | 98%min | ask | Career Henan Chemical Co |
-
- {4-[(Cyanomethyl)carbamoyl]phenyl}boronic acid
1056636-11-3
- US $3.00-9.00 / KG
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- 4-(cyanoMethylcarbaMoyl)phenylboronic acid
1056636-11-3
- US $2.00 / KG
- 98%min
- Career Henan Chemical Co
