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2-CHLORO-5-PHENYL-PYRIMIDINE

2-CHLORO-5-PHENYL-PYRIMIDINE Structure
2-CHLORO-5-PHENYL-PYRIMIDINE structure
CAS No.
22536-62-5
Chemical Name:
2-CHLORO-5-PHENYL-PYRIMIDINE
Synonyms
2-Chloro-5-phenyl-pyridimine;2-CHLORO-5-PHENYL-PYRIMIDINE;PyriMidine,2-chloro-5-phenyl-;2-CHLORO-5-PHENYL-PYRIMIDINE ISO 9001：2015 REACH
CBNumber:
CB4428455
Molecular Formula:
C10H7ClN2
Molecular Weight:
190.63
MDL Number:
MFCD04035567
MOL File:
22536-62-5.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:47
Product description Number Pack Size Price
2-chloro-5-phenylpyrimidine B428563 50mg $110
2-Chloro-5-phenylpyrimidine 95% OR938765 250mg $327
2-CHLORO-5-PHENYL-PYRIMIDINE 95.00% NUC0001548 5MG $501.88
2-Chloro-5-phenylpyrimidine 95% 3H32-5-MX 1g $888
2-Chloro-5-phenylpyrimidine 95% 3H32-5-MX 250mg $360
Request For Quotation

2-CHLORO-5-PHENYL-PYRIMIDINE Properties

Melting point 131-133 °C
Boiling point 369.9±21.0 °C(Predicted)
Density 1.245±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka -1.71±0.22(Predicted)
Appearance White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2933599590

2-CHLORO-5-PHENYL-PYRIMIDINE price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B428563 2-chloro-5-phenylpyrimidine 22536-62-5 50mg $110 2021-12-16 Buy
Apolloscientific OR938765 2-Chloro-5-phenylpyrimidine 95% 22536-62-5 250mg $327 2021-12-16 Buy
American Custom Chemicals Corporation NUC0001548 2-CHLORO-5-PHENYL-PYRIMIDINE 95.00% 22536-62-5 5MG $501.88 2021-12-16 Buy
SynQuest Laboratories 3H32-5-MX 2-Chloro-5-phenylpyrimidine 95% 22536-62-5 1g $888 2021-12-16 Buy
SynQuest Laboratories 3H32-5-MX 2-Chloro-5-phenylpyrimidine 95% 22536-62-5 250mg $360 2021-12-16 Buy
Product number Packaging Price Buy
B428563 50mg $110 Buy
OR938765 250mg $327 Buy
NUC0001548 5MG $501.88 Buy
3H32-5-MX 1g $888 Buy
3H32-5-MX 250mg $360 Buy

2-CHLORO-5-PHENYL-PYRIMIDINE Chemical Properties,Uses,Production

Application

2-Chloro-5-phenylpyrimidine can be used as an organic synthesis intermediate. It can be prepared by reacting 5-bromo-2-chloropyrimidine with Ph3In as a reactant, or by reacting 5-bromo-2-chloropyrimidine with phenylboronic acid via the Suzuki reaction.

Synthesis

5-Bromo-2-chloropyrimidine

32779-36-5

Phenylboronic acid

98-80-6

2-CHLORO-5-PHENYL-PYRIMIDINE

22536-62-5

General procedure: 5-bromo-2-chloropyrimidine (1 eq.), phenylboronic acid (1.1 eq.), Na2CO3 (1.1 eq.) and H2O (5 mL) were added to a round bottom flask, followed by catalyst (2 mol%). The reaction mixture was stirred at 45 °C until the reaction was complete. Upon completion of the reaction, the reaction mixture was diluted with water and the product was extracted with ethyl acetate. The ethyl acetate extract was filtered through a bed of diatomaceous earth and subsequently analyzed by GC. Retention times were verified using standards of 5-bromo-2-chloropyrimidine and 2-chloro-5-phenylpyrimidine to confirm product generation. The ethyl acetate extract was concentrated and purified by silica gel column chromatography using a solvent mixture of hexane and ethyl acetate as eluent to give 2-chloro-5-phenylpyrimidine. The product was characterized by NMR, GC-MS and UPLC analysis.

References

[1] Journal of Heterocyclic Chemistry, 2008, vol. 45, # 4, p. 1077 - 1081
[2] Journal of Molecular Catalysis A: Chemical, 2013, vol. 371, p. 118 - 124
[3] European Journal of Medicinal Chemistry, 2018, vol. 150, p. 30 - 38
[4] Patent: WO2004/22556, 2004, A1. Location in patent: Page 16-17

2-CHLORO-5-PHENYL-PYRIMIDINE synthesis

100-59-4
32779-36-5
22536-62-5
Synthesis of 2-CHLORO-5-PHENYL-PYRIMIDINE from PHENYLMAGNESIUM CHLORIDE and 5-Bromo-2-chloropyrimidine

2-CHLORO-5-PHENYL-PYRIMIDINE Preparation Products And Raw materials

Raw materials

1-Methyl-5-phenyl-2(1H)-pyrimidinone 5-PhenylpyriMidin-2(1H)-one Triphenylindium PHENYLMAGNESIUM CHLORIDE Phenylboronic acid
TRIBUTYLPHENYLTIN Benzene 5-Bromo-2-chloropyrimidine Water Sodium carbonate

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Preparation Products

2-CHLORO-5-PHENYL-PYRIMIDINE Suppliers

Global( 60)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29735 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-2158073036 info@dakenam.com China 13799 58
Hubei xin bonus chemical co. LTD 		86-13657291602 linda@hubeijusheng.com CHINA 22963 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29795 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		+8613580539051 joe@yuhengpharm.com CHINA 21142 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250 1026@dideu.com China 19282 58
DAYANG CHEM (HANGZHOU) CO.,LTD 		+86-88938639 +86-17705817739 info@dycnchem.com China 53899 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
ROSEWA HOLDING GROUP CO.,LIMITED 		+86-023-62871537 sales@rosewachem.com China 2813 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
Hubei xin bonus chemical co. LTD 		58
Alchem Pharmtech,Inc. 		58
career henan chemical co 		58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		58
Dideu Industries Group Limited 		58
DAYANG CHEM (HANGZHOU) CO.,LTD 		58
Amadis Chemical Company Limited 		58
ROSEWA HOLDING GROUP CO.,LIMITED 		58

View Lastest Price from 2-CHLORO-5-PHENYL-PYRIMIDINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-CHLORO-5-PHENYL-PYRIMIDINE pictures 2025-11-18 2-CHLORO-5-PHENYL-PYRIMIDINE
22536-62-5
 US $1.10 / g 1g 99.00% 100 Tons Min Dideu Industries Group Limited
2-CHLORO-5-PHENYL-PYRIMIDINE pictures 2020-01-09 2-CHLORO-5-PHENYL-PYRIMIDINE
22536-62-5
 US $1.00 / KG 1KG 95-99% 1ton Career Henan Chemical Co

2-CHLORO-5-PHENYL-PYRIMIDINE Spectrum

2-CHLORO-5-PHENYL-PYRIMIDINE(22536-62-5)1HNMR

22536-62-5(2-CHLORO-5-PHENYL-PYRIMIDINE)Related Search:

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2-CHLORO-5-PHENYL-PYRIMIDINE 2-Chloro-5-phenyl-pyridimine PyriMidine,2-chloro-5-phenyl- 2-CHLORO-5-PHENYL-PYRIMIDINE ISO 9001：2015 REACH 22536-62-5 pyrimidine Heterocycle-Pyrimidine series pharmacetical