16a,17a-Epoxyprogesterone
- CAS No.
- 1097-51-4
- Chemical Name:
- 16a,17a-Epoxyprogesterone
- Synonyms
- W-oxide;ZK-5197;Wobbe's oxide;Waugh's oxide;Albright oxide;Wolfowitz oxide;EPOXY PROGESTERONE;16a,17a-Epoxyprogest;16,17-EPOXYPROGESTERONE;16-17A-Epoxyprogesterone
- CBNumber:
- CB8156077
- Molecular Formula:
- C21H28O3
- Molecular Weight:
- 328.45
- MDL Number:
- MFCD00055948
- MOL File:
- 1097-51-4.mol
| Product description | Number | Pack Size | Price |
| 16α,17α-Epoxyprogesterone | E589580 | 25g | $250 |
| 16α,17α-Epoxyprogesterone | 94327 | 2.5g | $375 |
| 16,17-ALPHA-EPOXYPROGESTERONE 95.00% | CHM0017583 | 5MG | $550 |
| 16,17-ALPHA-EPOXYPROGESTERONE 95.00% | CHM0017583 | 1G | $945.95 |
| 16,17-ALPHA-EPOXYPROGESTERONE 95.00% | CHM0017583 | 5G | $1370.41 |
| More product size | |||
| Melting point | 200C |
|---|---|
| Boiling point | 466.9±45.0 °C(Predicted) |
| Density | 1.18±0.1 g/cm3(Predicted) |
| refractive index | 168 ° (C=1, CHCl3) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | Chloroform, Methanol |
| form | Solid |
| color | Off-White |
| CAS DataBase Reference | 1097-51-4(CAS DataBase Reference) |
| FDA UNII | F2DR02G069 |
16a,17a-Epoxyprogesterone price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | E589580 | 16α,17α-Epoxyprogesterone | 1097-51-4 | 25g | $250 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 94327 | 16α,17α-Epoxyprogesterone | 1097-51-4 | 2.5g | $375 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0017583 | 16,17-ALPHA-EPOXYPROGESTERONE 95.00% | 1097-51-4 | 5MG | $550 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0017583 | 16,17-ALPHA-EPOXYPROGESTERONE 95.00% | 1097-51-4 | 1G | $945.95 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0017583 | 16,17-ALPHA-EPOXYPROGESTERONE 95.00% | 1097-51-4 | 5G | $1370.41 | 2021-12-16 | Buy |
16a,17a-Epoxyprogesterone Chemical Properties,Uses,Production
Uses
16α,17α-Epoxyprogesterone is hydrolyzed by Rhizopus nigricans for the synthesis of many steroidal drugs.
Definition
ChEBI: 16-alpha,17-Epoxypregn-4-ene-3,20-dione is a corticosteroid hormone.
Synthesis
2872-76-6
1097-51-4
The general procedure for the synthesis of 16,17-epoxyprogesterone from the compound (CAS: 2872-76-6) was as follows: 0.496 g of compound (III) (1.5 × 10^-3 mol) was dissolved in 30 mL of acetone and the reaction system was cooled to 0 °C. Subsequently, 0.48 mL of conditioned Jones' reagent was slowly added (preparation of Jones' reagent: 2.67 g of CrO3 was dissolved in 2.3 mL of concentrated sulfuric acid and then diluted to 10 mL with water). After stirring the reaction mixture for 1 h at 0 °C, the progress of the reaction was monitored by thin layer chromatography (TLC) until the reaction was completed. Upon completion of the reaction, 0.5 mL of isopropanol was added to the system to quench the reaction, followed by distillation under reduced pressure to remove the acetone. The reaction mixture was extracted three times with 20 mL of ethyl acetate and the organic phases were combined. The organic phase was washed sequentially with saturated sodium bicarbonate solution and saturated brine, and then dried over anhydrous sodium sulfate. The dried organic phase was concentrated under reduced pressure and the resulting residue was purified by column chromatography to afford 0.446 g of white solid 16α,17α-epoxypregn-4-ene-3,20-dione (IV) in 90.6% isolated yield.
References
[1] Patent: CN104610421, 2017, B. Location in patent: Paragraph 0015; 0036; 0037; 0038; 0039
16a,17a-Epoxyprogesterone Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
1of3
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21612 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 | info@tnjchem.com | China | 2988 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29847 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Cangzhou Wanyou New Material Technology Co.,Ltd | 18631714998 | sales@czwytech.com | CHINA | 904 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-17392712697 | 1022@dideu.com | China | 3995 | 58 |
| Nanjing Shizhou Biotechnology Co., Ltd | +86-15850508050 | sean.lv@synzest.com | China | 323 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32435 | 58 |
View Lastest Price from 16a,17a-Epoxyprogesterone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-05 | 16a,17a-Epoxy-4-Pregnen-3,20-Dione
1097-51-4
|
US $29.00 / mL | 99.89% | 10g | TargetMol Chemicals Inc. | ||
 |
2021-12-23 | 16a,17a-Epoxyprogesterone
1097-51-4
|
US $0.00 / GK | 1g | 99% | 5kg | WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD | |
 |
2020-07-08 | 16a,17a-Epoxyprogesterone
1097-51-4
|
US $665.00 / KG | 1KG | 98.0% | 1T | Shaanxi Dideu Medichem Co. Ltd |
-
- 16a,17a-Epoxy-4-Pregnen-3,20-Dione
1097-51-4
- US $29.00 / mL
- 99.89%
- TargetMol Chemicals Inc.
-
- 16a,17a-Epoxyprogesterone
1097-51-4
- US $0.00 / GK
- 99%
- WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
-
- 16a,17a-Epoxyprogesterone
1097-51-4
- US $665.00 / KG
- 98.0%
- Shaanxi Dideu Medichem Co. Ltd
