HIV-1 Tat Protein (47-57)
|
|
HIV-1 Tat Protein (47-57) 속성
- 녹는점
- 202-203 °C
- 밀도
- 1.54±0.1 g/cm3(Predicted)
- 저장 조건
- -20°C
- 용해도
- 탈이온수: 가용성
- 물리적 상태
- 동결건조된 분말
- 생물학적 소스
- synthetic
- 수용성
- deionized water: soluble
- 시퀀스
- Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg
- InChIKey
- RAVVEEJGALCVIN-AGVBWZICSA-N
안전
| WGK 독일 | nwg |
|---|
HIV-1 Tat Protein (47-57) C화학적 특성, 용도, 생산
용도
TAT (YGRKKRRQRRR) is derived from the transactivator of transcription (TAT) of human immunodeficiency virus-1 (HIV-1) and is a cell-penetrating peptide. TAT can increase the yields and the solubility of heterologous proteins일반 설명
HIV-1 trans-activator of transcription (Tat) is an 11kDa protein, which regulates HIV-1 gene expression at the level of transcription and protein synthesis. It is located in the nucleus of infected cells. HIV-1 Tat functions as a transcriptional activator for the synthesis of full-length viral RNA. It induces RNA splicing. Tat is an RNA binding protein, which particularly recognizes trans activator response element (TAR) from the HIV-1 RNA molecule.Biochem/physiol Actions
Synthetic peptide that includes the sequence responsible for the cellular uptake of the human immunodeficiency virus-1 Tat protein, consisting of the polycationic region 49–57. The peptide is part of the protein transduction domain (PTD) and was shown to enable the introduction of nucleic acids into cells.참고 문헌
[1] NICOLAS CHARNAY. Mechanism of HIV-1 Tat RNA translation and its activation by the Tat protein.[J]. ACS Applied Bio Materials, 2009: 74. DOI:10.1186/1742-4690-6-74.[2] ASEN BAGASHEV Bassel E S. Roles and functions of HIV-1 Tat protein in the CNS: an overview.[J]. ACS Applied Energy Materials, 2013: 358. DOI:10.1186/1743-422X-10-358.
[3] NANCY MUELLER. The HIV-1 Tat Protein Enhances Splicing at the Major Splice Donor Site.[J]. ACS Applied Energy Materials, 2018. DOI:10.1128/JVI.01855-17.
[4] ESTEBAN CRUZ Veysel K. Synthesis and Enhanced Cellular Uptake In Vitro of Anti-HER2 Multifunctional Gold Nanoparticles.[J]. ACS Applied Energy Materials, 2019. DOI:10.3390/cancers11060870.
[5] ANDRé ZIEGLER Joachim S. Interaction of the protein transduction domain of HIV-1 TAT with heparan sulfate: binding mechanism and thermodynamic parameters.[J]. Biophysical journal, 2004, 86 1 Pt 1: 254-263. DOI:10.1016/S0006-3495(04)74101-6.
HIV-1 Tat Protein (47-57) 준비 용품 및 원자재
원자재
준비 용품
HIV-1 Tat Protein (47-57) 공급 업체
글로벌( 121)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 |
faithe@yan-xi.com | China | 5853 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 33024 | 60 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 |
admin@nexconn.com | China | 10405 | 58 |
| BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19552 | 58 |
| Shanghai Longyu Biotechnology Co., Ltd. | +8619521488211 |
info@longyupharma.com | China | 2541 | 58 |
| Cellmano Biotech Limited | 0551-65326643 18156095617 |
info@cellmano.com | China | 995 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 |
factory@coreychem.com | China | 29795 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 |
1026@dideu.com | China | 19182 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471; |
sales@sarms4muscle.com | China | 10473 | 58 |
| Hangzhou Go Top Peptide Biotech | 0571-88211921 |
sales1@gotopbio.com | CHINA | 2609 | 58 |