Bendamustine hydrochloride
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Bendamustine hydrochloride 속성
- 녹는점
- 149-151°C
- 저장 조건
- room temp
- 용해도
- H2O: >30mg/mL
- 물리적 상태
- 가루
- 색상
- 회백색
- Merck
- 14,1034
- InChI
- InChI=1S/C16H21Cl2N3O2.ClH/c1-20-14-6-5-12(21(9-7-17)10-8-18)11-13(14)19-15(20)3-2-4-16(22)23;/h5-6,11H,2-4,7-10H2,1H3,(H,22,23);1H
- InChIKey
- ZHSKUOZOLHMKEA-UHFFFAOYSA-N
- SMILES
- C12N=C(CCCC(=O)O)N(C)C=1C=CC(N(CCCl)CCCl)=C2.Cl
- CAS 데이터베이스
- 3543-75-7(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | T,Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 60-61-22-40 | ||
| 안전지침서 | 36-37 | ||
| 유엔번호(UN No.) | UN 2811 6.1 / PGIII | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | DE1590000 | ||
| 위험 등급 | 6.1 | ||
| 포장분류 | III | ||
| HS 번호 | 29339900 | ||
| 독성 | LD50 (monohydrate) in mice, rats (mg/kg): 400-500, 200-300 orally; 80, 40 i.v. (Horn) |
Bendamustine hydrochloride C화학적 특성, 용도, 생산
화학적 성질
Pale Brown Crystals용도
Bendamustine hydrochloride hydrate has been used as:- a chemotherapy agent for chronic lymphocytic leukemia (CLL) samples to monitor spliced and unspliced gene expression
- an inhibitor to E3 ubiquitin-protein ligase RNF3 (HOIP) in?matrix-assisted laser desorption ionization time-of-flight mass spectrometry?(MALDI-TOF) assay
- a cytotoxic chemotherapeutic drug in high-throughput screening to test interaction with BAY87-2243
일반 설명
Bendamustine comprises 2-chloroethylamine alkylating group, a butyric acid side chain and a benzimidazole ring in its structure and is a nitrogen mustard. It is catabolized in the liver by the enzyme cytochrome P450 1A2 into γ hydroxyl-bendamustine and N-desmethyl-bendamustine.생물학적 활성
Cytostatic agent that displays activity in non-Hodgkin's lymphomas. Exhibits bifunctionality; combines DNA alkylating properties with those of purine analogs.Bendamustine hydrochloride 준비 용품 및 원자재
원자재
Pentanoic acid, 5-[(2,4-dinitrophenyl)methylamino]-5-oxo-, methyl ester
Pentanoic acid, 5-[(2,4-dinitrophenyl)amino]-5-oxo-, methyl ester
isopropyl 4-(1-methyl-5-nitro-1H-benzo[d]imidazol-2-yl)butanoate
5-[비스(2-클로로에틸)아미노]-1-메틸-1H-벤즈이미다졸-2-부탄산메틸에스테르
1H-Benzimidazole-2-butanoic acid, 5-[bis(2-hydroxyethyl)amino]-1-methyl-, 1-methylethyl ester
1-클로로-2.4-디니트로벤젠
5-[비스(2-하이드록시에틸)아미노]-1-메틸-1H-벤즈이미다졸-2-부탄산에틸에스테르
Methyl 4-(chloroformyl)butyrate
BendaMustine IMpurity C
2,4-디니트로아닐린
5-[비스(2-히드록시에틸)아미노]-1-메틸-1H-벤즈이미다졸-2-부탄산메틸에스테르
N-메틸-2,4-디니트로아닐린
N1-메틸-4-니트로-o-페닐디아민
준비 용품
Bendamustine hydrochloride 공급 업체
글로벌( 452)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 |
Sibel@chuanghaibio.com | China | 8768 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-173 9270 1263 |
1057@dideu.com | China | 3999 | 58 |
| BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD. | +86-18600796368 |
sales@sjar-tech.com | China | 504 | 58 |
| Shaanxi Xianhe Biotech Co., Ltd | +86-17709210191; +8617709210191 |
Jerry@xhobio.com | China | 883 | 58 |
| Wuhan JiyunZen Tech Co., Ltd. | +86-18062099985 |
Amyjiyunzen@yeah.net | China | 672 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 |
sales@capot.com | China | 29735 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21612 | 55 |
| Lianyungang happen teng technology co., LTD | 15950718863 |
wang666xt@163.com | CHINA | 295 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29847 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22963 | 58 |
Bendamustine hydrochloride 관련 검색:
이브루티니브 시클로헥실아민염산염 메클레타민 수화염화물 1-메틸-1H-벤조이미다졸-5-일라민삼수화염 4-(2-BENZIMIDAZOLYL)부티르산 벤다무스틴-D8염산염
Olaparib
CAL-101
Lenalidomide
ABT-199
Bortezomib
Sofosbuvir
Aprepitant
5-[bis-(2-Chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid ethyl ester
5-[(2-Chloroethyl)(2-hydroxyethyl)aMino]-1-Methyl-1H-benziMidazole-2-butanoic Acid
5-[(2-Chloroethyl)(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid 1-Methylethyl Ester
BroMo Prasugrel IMpurity
AMbroxoliMpurity