1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one
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1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one 속성
- 녹는점
- 86-88
- 끓는 점
- 281.4±36.0 °C(Predicted)
- 밀도
- 1.070±0.06 g/cm3(Predicted)
- 증기압
- 0.049Pa at 20℃
- 저장 조건
- Inert atmosphere,Room Temperature
- 용해도
- 클로로포름과 디클로로메탄에 용해됩니다.
- 산도 계수 (pKa)
- 6.19±0.70(Predicted)
- 물리적 상태
- powder to crystal
- 색상
- 밝은 노란색에서 갈색까지
- InChI
- InChI=1S/C10H12N2O/c1-12(2)7-5-10(13)9-4-3-6-11-8-9/h3-8H,1-2H3
- InChIKey
- MZLRFUCMBQWLNV-FNORWQNLSA-N
- SMILES
- C(C1=CC=CN=C1)(=O)C=CN(C)C
- LogP
- 0.26 at 20℃ and pH7.2
- 표면장력
- 71.8mN/m at 1.008g/L and 20℃
- CAS 데이터베이스
- 55314-16-4(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi,Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 22-36/37/38 | ||
| 안전지침서 | 26-36/37/39 | ||
| 위험 등급 | IRRITANT | ||
| HS 번호 | 29333990 |
1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one C화학적 특성, 용도, 생산
개요
1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one can be used in the synthesis of imatinib and nilotinib (AMN107), a compound currently in multiple Phase II/III clinical trials for chronic granulocytic leukaemia. Imatinib, on the other hand, is a cancer growth blocker known as a tyrosine kinase inhibitor (TKI), which is used to treat a wide range of leukaemias, myelodysplastic/myeloproliferative disorders, systemic mastocytosis, eosinophilia syndromes, raised dermal fibrosarcoma and gastrointestinal mesenchymal tumours.화학적 성질
Off-White SolidSolubility in organics
1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one is soluble in Chloroform and Dichloromethane.1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one 준비 용품 및 원자재
원자재
준비 용품
1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one 공급 업체
글로벌( 267)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Yangzhou Qinyuan Pharmatech Co.,ltd | +86-18752526868 +86-18752526868 |
jennysun@yzqyyykj.com | China | 83 | 58 |
| QUALITY CONTROL SOLUTIONS LTD. | +86-0755-66853366 +86-13670046396 |
export03@qcsrm.com | China | 24342 | 58 |
| Shandong Jihui Chemical Co., Ltd. | +8615053042019 |
sales@jihuichem.com | China | 34 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 |
sales@capot.com | China | 29735 | 60 |
| Hi-Tech Chemistry Corp | 0519-86626038 |
yuhh@hitechem.com | CHINA | 810 | 58 |
| Anqing Chico Pharmaceutical Co., Ltd. | 15380796838 |
chloewu@chicopharm.cn | CHINA | 340 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29850 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 |
sales@finerchem.com | China | 2954 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 |
sale@chuangyingchem.com | CHINA | 5906 | 58 |
1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one 관련 검색:
3-(디메틸아미노)프로필아민 P-다이메틸아미노벤즈알데하이드 4-다이메틸아미노피리딘 2-아미노피리딘 3-아미노피리딘 4-다이메틸아미노벤조산 ImatinibMeta-methyl-piperazine불순물 1-[2-[BIS(TERT-BUTYL)PHOSPHINO]페닐]-3,5-디페닐-1H-피라졸 1-(2,3-디클로로페닐)피페라진염산염 4-(4-메틸피페라진-1-일메틸)벤조산 4-브로모메틸벤조산 4-[(4-메틸피페라진-1-일)메틸]벤조산이염산염 2-메틸-5-니트로아닐린 이마티닙-d8 4-(피페라진-1-일메틸)벤조산 1-(1-옥시도-3-피리디닐)-에타논 iMatinib관련물질C N-(3-GUANIDINO-4-메틸페닐)-4-(메틸피페라진-1-YL-메틸)벤즈아미드