Adenanthin
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Adenanthin 속성
- 끓는 점
- 593.4±50.0 °C(Predicted)
- 밀도
- 1.29±0.1 g/cm3(Predicted)
- 산도 계수 (pKa)
- 14.13±0.70(Predicted)
안전
Adenanthin C화학적 특성, 용도, 생산
효소 저해제
This diterpenoid (FW = 484.63 g/mol; CAS 111917-59-0) from the leaves of Rabdosia adenantha, induces differentiation of acute promyelocytic leukemia (APL) cells. Adenanthin targets the conserved cysteine thiols of peroxiredoxins I and II (or Prx I and Prx II), inhibiting their peroxidase activities and consequently increasing cellular hydrogen peroxide. The latter leads to the activation of Extracellular signal-Regulated Kinases (ERKs) and increased transcription of CCAAT/enhancer-binding protein β (or C/EBPs), further contributing to differentiation. Adenanthin induces APL-like cell differentiation, represses tumor growth in vivo and prolongs the survival of mouse APL models that are sensitive and resistant to retinoic acid.Adenanthin 준비 용품 및 원자재
원자재
준비 용품
Adenanthin 공급 업체
글로벌( 62)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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| BOC Sciences | +1-631-485-4226 |
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| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 |
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| Aktin Chemicals, Inc. | 028-85159085 |
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| Labnetwork lnc. | +86-27-50766799 +8618062016861 |
contact@labnetwork.com | China | 19987 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 |
product@acmec-e.com | China | 33325 | 58 |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 |
cooperation@kean-chem.com | China | 40066 | 58 |
| Chembest Research Laboratories Limited | +86-21-20908456 |
sales@BioChemBest.com | China | 6003 | 61 |
| BioBioPha Co., Ltd. | 0871-65217109 13211707573; |
y.liu@mail.biobiopha.com | China | 5645 | 65 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 |
3003855609@qq.com | China | 7778 | 56 |
| Wuxi Zhongkun Biochemical Technology Co., Ltd. | 0510-85629785 18013409632 |
sales@reading-chemicals.com | China | 15178 | 58 |