ChemicalBook >제품 카탈로그 >SR 16832

SR 16832

SR 16832 구조식 이미지

카스 번호:: 2088135-12-8

상품명:: SR 16832

동의어(영문):: SR 16832;2-Chloro-N-(6-methoxy-4-quinolinyl)-5-nitrobenzamide;2-Chloro-N-(6-methoxyquinolin-4-yl)-5-nitrobenzamide;Benzamide, 2-chloro-N-(6-methoxy-4-quinolinyl)-5-nitro-;inhibit,Inhibitor,SR 16832,Peroxisome proliferator-activated receptors,PPAR

CBNumber:: CB64902739

분자식:: C17H12ClN3O4

포뮬러 무게:: 357.75

MOL 파일:: 2088135-12-8.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 36

SR 16832 속성

끓는 점: 492.3±45.0 °C(Predicted)

밀도: 1.469±0.06 g/cm3(Predicted)

저장 조건: Store at -20°C

용해도: DMSO: 용해될 수 있다

물리적 상태: 결정성 고체

산도 계수 (pKa): 9.71±0.43(Predicted)

색상: White to off-white

InChI: InChI=1S/C17H12ClN3O4/c1-25-11-3-5-15-13(9-11)16(6-7-19-15)20-17(22)12-8-10(21(23)24)2-4-14(12)18/h2-9H,1H3,(H,19,20,22)

InChIKey: CVTZAGCRUDYUGB-UHFFFAOYSA-N

SMILES: C(NC1C2C(N=CC=1)=CC=C(OC)C=2)(=O)C1=CC([N+]([O-])=O)=CC=C1Cl

안전

WGK 독일	WGK 3
스토리지 클래스	11 - Combustible Solids

SR 16832 C화학적 특성, 용도, 생산

개요

SR 16832 is a dual-site covalent antagonist of peroxisome proliferator-activated receptor γ (PPARγ). It inhibits MRL20-induced allosteric activation of PPARγ in a reporter assay using HEK293T cells when used at a concentration of 5 μM. SR 16832 also reduces basal activity of PPARγ and inhibits binding of docosahexaenoic acid to PPARγ in a time-resolved FRET (TR-FRET) assay.

용도

SR 16832 is a dual site PPARγ inhibitor. Acts at orthosteric and allosteric sites in the ligand binding domain. Inhibits binding of endogenous ligands and transcriptional activity of PPARγ, more effectively than the orthosteric covalent antagonists.

SR 16832 준비 용품 및 원자재

원자재

준비 용품

SR 16832 공급 업체

글로벌( 36)공급 업체

공급자	전화	이메일	국가	제품 수	이점
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32470	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58
Nanjing Chemlin Chemical Co., Ltd	025-83697070	info@chemlin.com.cn	China	15724	64
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9803	58
Shanghai YuanYe Biotechnology Co., Ltd.	021-61312847; 18021002903	3008007409@qq.com	China	71615	60
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6777	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11218	58
ShangHai ChuanQian Chemcial Technique Centre	15869524721	3525679403@qq.com	China	4998	58
Jinan Jiuli Biotechnology Co. , Ltd.	15865264761	486064515@qq.com	China	4873	58

SR 16832 관련 검색:

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