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Lotilaner

Lotilaner 구조식 이미지

카스 번호:: 1369852-71-0

상품명:: Lotilaner

동의어(영문):: Lothilana;Lotilaner;D4-Lotilaner;Lotilaner (TP-05);Lotilaner Impurity2;Lotilaner, 10 mM in DMSO;Parasite,Inhibitor,γ-Aminobutyric acid Receptor,Lotilaner,inhibit,Gamma-aminobutyric acid Receptor,GABA Receptor;(S)-3-Methyl-N-(2-oxo-2-((2,2,2-trifluoroethyl)a mino)ethyl)-5-(5-(3,4,5-trichlorophenyl)-5-(trifluo romethyl)-4,5-dihydroisoxazol-3-yl)thiophene-2- carboxamide;2-Thiophenecarboxamide, 5-[(5S)-4,5-dihydro-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-3-isoxazolyl]-3-methyl-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-;(S)-5-[5-(3,4,5-trichloro-phenyl)-5-trifluoromethyl-4,5-dihydro-isoxazol-3-yl]-3-methyl-thiophene-2-carboxylic acid [(2,2,2-trifluoro-ethylcarbamoyl)-methyl]-amide

CBNumber:: CB73344768

분자식:: C20H14Cl3F6N3O3S

포뮬러 무게:: 596.76

MOL 파일:: 1369852-71-0.mol

속성

안전

용도

공급 업체 110

Lotilaner 속성

밀도: 1.66±0.1 g/cm3(Predicted)

저장 조건: Store at -20°C

용해도: DMSO : ≥ 100 mg/mL (167.57 mM)

물리적 상태: Solid

산도 계수 (pKa): 12.52±0.46(Predicted)

색상: White to off-white

InChIKey: HDKWFBCPLKNOCK-SFHVURJKSA-N

SMILES: C1(C(NCC(=O)NCC(F)(F)F)=O)SC(C2C[C@](C3=CC(Cl)=C(Cl)C(Cl)=C3)(C(F)(F)F)ON=2)=CC=1C

안전

Lotilaner C화학적 특성, 용도, 생산

개요

Lotilaner is a representative of the isoxazolines, a new class of insecticides discovered in the 2000s.
Isoxazolines (Afoxolaner, Fluralaner, Lotilaner, and Sarolaner) Isoxazolines are insecticidal and arachnicidal substances that can be given orally, or topically as spot-ons, and act systemically in the blood circulation.
lotilaner (Credeliot), a novel oral isoxazoline against naturally occurring mange mite infestations in dogs caused by Demodex spp.
Lotilaner, like the other isooxazolines is active against fleas, mites, and ticks. After oral administration or topical application, it can kill fleas rapidly.

용도

Lotilaner is a new member of the isoxazoline class for the treatment of flea and tick infestations in cats.

Indications

Lotilaner is a monthly chewable tablet for the treatment and prevention of fleas and ticks. It is used in dogs and puppies 8 weeks of age or older weighing 4.4 pounds or greater (Elanco, 2019).

부작용

These include weight loss, elevated blood urea nitrogen, increased urination, and diarrhea (Elanco, 2019).

Lotilaner 준비 용품 및 원자재

원자재

2-Thiophenecarboxylic acid, 5-[4,5-dihydro-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-3-isoxazolyl]-3-methyl- Isoxazole, 3-(5-bromo-4-methyl-2-thienyl)-4,5-dihydro-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)- 5-BROMO-3-METHYLTHIOPHENE-2-CARBOXYLIC ACID 2-아미노-N-(2,2,2-트리플루오로에틸)아세트아미드염산염

준비 용품

Lotilaner 공급 업체

글로벌( 110)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Jinan Hong Kongda Chemical Co.,LTD	+undefined18753193522	sales@hkdchem.com	China	108	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-81148696 +86-17392712697	1022@dideu.com	China	3994	58
Jinan Million Pharmaceutical Co., Ltd	0531-68659554 +8613031714605	info@millionpharm.com	China	208	58
Wuhan JiyunZen Tech Co., Ltd.	+86-18062099985	Amyjiyunzen@yeah.net	China	672	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	+86-13017695106 +86-13676922317	jiuyitime@fdachem.com	China	16513	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	11767	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32435	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30229	58
Shanghai UCHEM Inc.	+862156762820 +86-13564624040	sales@myuchem.com	China	8460	58