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Gap19

Gap19 구조식 이미지

카스 번호:: 1507930-57-5

상품명:: Gap19

동의어(영문):: Gap19;KQIEIKKFK;Gap19 ，S6946;GAP19 Trifluoroacetate;L-Lysine, L-lysyl-L-glutaminyl-L-isoleucyl-L-α-glutamyl-L-isoleucyl-L-lysyl-L-lysyl-L-phenylalanyl-;myocardial,Gap19,cytoplasmic,Cx40/pannexin-1,inhibit,Gap Junction Protein,C-terminus,Gap 19,hemichannel,Inhibitor,loop,Gap-19,Cx43,channels,connexin;(2S,5S,8S,11S,14S,17S)-17-((2S,3S)-2-((S)-5-Amino-2-((S)-2,6-diaminohexanamido)-5-oxopentanamido)-3-methylpentanamido)-2,8,11-tris(4-aminobutyl)-5-benzyl-14-((S)-sec-butyl)-4,7,10,13,16-pentaoxo-3,6,9,12,15-pentaazaicosane-1,20-dioic acid;(2S,5S,8S,11S,14S,17S)-17-((2S,3S)-2-((S)-5-Amino-2-((S)-2,6-diaminohexanamido)-5-oxopentanamido)-3-methylpentanamido)-2,8,11-tris(4-aminobutyl)-5-benzyl-14-((S)-sec-butyl)-4,7,10,13,16-pentaoxo-3,6,9,12,15-pentaazaicosane-1,20-dioic acid , Gap19

CBNumber:: CB94632530

분자식:: C55H96N14O13

포뮬러 무게:: 1161.46

MOL 파일:: 1507930-57-5.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 72

Gap19 속성

끓는 점: 1511.4±65.0 °C(Predicted)

밀도: 1.212±0.06 g/cm3(Predicted)

저장 조건: -20°C

용해도: ≥58.07 mg/mL in H2O; insoluble in EtOH; ≥26.55 mg/mL in DMSO

산도 계수 (pKa): 3.30±0.10(Predicted)

물리적 상태: 가루

색상: 흰색에서 황백색까지

수용성: 물에 2mg/ml까지 용해됨

InChIKey: IEAKEKFIXUZWEH-PKMKMBMKSA-N

안전

WGK 독일	WGK 3
스토리지 클래스	11 - Combustible Solids

Gap19 C화학적 특성, 용도, 생산

용도

Gap19 is a short peptide that inhibits hemichannels specifically for connexin-43 (Cx43), a cardiac connexin involved with gap junction formation. Gap junctions facilitate the exchange of ions and metabolites between cytoplasm and extracellular milieu. Reagents that inhibit hemichannels may have cardioprotective properties.

Biochem/physiol Actions

Gap19, nonapeptide from the cytoplasmic loop of Connexin-43, is a selective blocker of connexin 43 (Cx43) hemichannel that does not block GJ or Cx40/Panx-1 channels in cardiomyocytes and astrocytes. Gap19 prevents Cx43 hemichannel opening and protect against myocardial ischemia/reperfusion injury.

Gap19 준비 용품 및 원자재

원자재

준비 용품

Gap19 공급 업체

글로벌( 72)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10405	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30229	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471;	sales@sarms4muscle.com	China	10473	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	39042	58
Nanjing TGpeptide	+86-13347807150	support@tgpeptide.com	China	3279	58
Sichuan Jisheng Biopharmaceutical	+86-0833-2598903 +8619981963231	jane@jsjpharm.cn	China	173	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58
Changsha MOL Changes Biotechnology Co., Ltd.	+8619375158599	info@molchanges.com	China	5218	58
ShangHai Caerulum Pharma Discovery Co., Ltd.	18149758185 18149758185;	sales-cpd@caerulumpharma.com	China	3505	58