6-tert-Butyl-2,3-naphthalenedicarbonitrile manufacturers
- BRD9876
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- $82.00 / 500mg
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2026-04-22
- CAS:32703-82-5
- Min. Order:
- Purity: 97.81%
- Supply Ability: 10g
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| | 6-tert-Butyl-2,3-naphthalenedicarbonitrile Basic information |
| Product Name: | 6-tert-Butyl-2,3-naphthalenedicarbonitrile | | Synonyms: | LABOTEST-BB LT00159322;6-TERT-BUTYL-2,3-NAPHTHALENEDICARBONITRILE;2,3-Dicyano-6-tert-butylnaphthalene;6-tert-Butyl-2,3-dicyanonaphthalene;6-tert-Butyl-2,3-naphthalodinitrile;2,3-NAPHTHALENEDICARBONITRILE, 6-(1,1-DIMETHYLETHYL)-;6-(1,1-Dimethylethyl)-2,3-naphthalenedicarbonitrile;6-tert-butyl-2,3-naphthalonitrile | | CAS: | 32703-82-5 | | MF: | C16H14N2 | | MW: | 234.3 | | EINECS: | | | Product Categories: | B;Stains and Dyes;Stains&Dyes, A to | | Mol File: | 32703-82-5.mol |  |
| | 6-tert-Butyl-2,3-naphthalenedicarbonitrile Chemical Properties |
| Melting point | 185-189 °C(lit.) | | Boiling point | 429.7±33.0 °C(Predicted) | | density | 1.11±0.1 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | solubility | Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly) | | form | Solid | | color | Pale Yellow to Light Beige | | Major Application | diagnostic assay manufacturing
hematology
histology | | InChI | InChI=1S/C16H14N2/c1-16(2,3)15-5-4-11-6-13(9-17)14(10-18)7-12(11)8-15/h4-8H,1-3H3 | | InChIKey | MKILROQBJOOZKC-UHFFFAOYSA-N | | SMILES | C1=C2C(C=C(C(C)(C)C)C=C2)=CC(C#N)=C1C#N |
| Hazard Codes | Xn | | Risk Statements | 20/21/22 | | Safety Statements | 36 | | WGK Germany | 3 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral |
| | 6-tert-Butyl-2,3-naphthalenedicarbonitrile Usage And Synthesis |
| Uses | 6-tert-Butyl-2,3-naphthalenedicarbonitrile is a stain with bioloigcal research applications. Dyes and metabolites. | | Definition | ChEBI: 6-tert-butylnaphthalene-2,3-dicarbonitrile is a member of naphthalenes. | | Biological Activity | BRD9876 is an inhibitor of the kinesin spindle protein Eg5. It arrests Eg5-mediated microtubule gliding, as well as inhibits Eg5 ATPase activity in the presence of microtubules, in cell-free assays. BRD9876 is cytotoxic to MM.1S stroma-independent multiple myeloma cells (IC50 = 2.2 μM). It induces cell cycle arrest at the G2/M phase in MM.1S cells when used at a concentration of 10 μM. | | References | [1] SHRIKANTA CHATTOPADHYAY. Niche-Based Screening in Multiple Myeloma Identifies a Kinesin-5 Inhibitor with Improved Selectivity over Hematopoietic Progenitors.[J]. Cell reports, 2015, 10 5: 755-770. DOI: 10.1016/j.celrep.2015.01.017 |
| | 6-tert-Butyl-2,3-naphthalenedicarbonitrile Preparation Products And Raw materials |
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