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异噻唑啉酮类化合物是一类广谱高效的工业杀菌防霉剂。 本文合成的N –甲基- 1 ,2 -苯并异噻唑啉- 3 - 酮是一个新的化合物,其合成方法国内外鲜见有关文献专门报道。经过探索性研究,确定由邻氨基苯甲酸为原料,经重氮盐二硫代,酰氯化,甲氨基取代和碱性闭环4 步得到目标分子的合成路线。产物结构经红外光谱及核磁共振谱确认。 关键词:苯并异噻唑啉酮 重氮盐硫代 二硫二苯甲酰氯 2 - 硫溴苯甲酰氯;环合 杀菌剂 防霉剂
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Vary thiazole-ketones is a kind of broad-spectrum efficient industrial sterilization Fungicides. This article of the N - methyl - 1, 2 - benzo vary thiazole-- 3 - one is a new compound, the synthesis of the literature at home and abroad uncommon for special reports. After exploratory studies to determine the anthranilic acid as raw materials, the diazonium salt dithiocarbamate, chloride, a closed-loop and basic amino replace Step 4 by the objective elements of the road. The structures of the IR and NMR confirmed. Key words: benzo vary thiazole-one diazonium salt S disulfide two benzoyl chloride 2 - sulfur bromine benzoyl chloride; ring a fungicide Fungicides
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The different sai zuo lin ketones compound is a kind of broad spectrum highly effective industry sterilization antiseptic. This article synthesizes N - methyl - 1, 2 - benzene and the different sai zuo lin - 3 - alkone are new compound, its synthetic method domestic and foreign rarely seen related literature reported specially. After the exploring research, determined that by the neighbouring benzaminic acid is raw material, after the diazo salt dithio-, the acid radical chlorination, the armor amino substitution and the alkalinity closed loop 4 steps obtains the goal member process of synthesis. Product structure after infrared spectrum and nuclear magnetic resonance spectrum confirmation.
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