1234903-01-5 ((5-AZIDOPYRIMIDINE)

快速询单

结构式：

5-AZIDOPYRIMIDINEMOL文件

CAS号：

1234903-01-5

英文名称：

5-AZIDOPYRIMIDINE

分子式：

C₄H₃N₅

分子量：

121.100118875504

5-AZIDOPYRIMIDINE(1234903-01-5)名称与标识符

名称

英文别名：

5-Azidopyrimidine (ACI);Pyrimidine, 5-azido- (ACI);5-AZIDOPYRIMIDINE;

标识符

MDL：

MFCD24457796

InChIKey：

UCPNZTZUYHRUPQ-UHFFFAOYSA-N

Inchi：

1S/C4H3N5/c5-9-8-4-1-6-3-7-2-4/h1-3H

SMILES：

[N-]=[N+]=NC1C=NC=NC=1

5-AZIDOPYRIMIDINE(1234903-01-5)合成路线

合成路线：1 步

109299-78-7

_63%

1234903-01-5

反应条件：

1.1 Reagents: Sodium azide Catalysts: Copper sulfate Solvents: Methanol ; rt

参考文献：

Steering the azido-tetrazole equilibrium of 4-azidopyrimidines via substituent variation - implications for drug design and azide-alkyne cycloadditions

Thomann, A.; et al, Organic & Biomolecular Chemistry, 2015, 13(43), 10620-10630

合成路线：1 步

109299-78-7

_48%

1234903-01-5

反应条件：

1.1 Reagents: Sodium azide Catalysts: Cupric acetate Solvents: Methanol ; 24 h, 55 °C

参考文献：

Copper(II)-catalyzed conversion of aryl/heteroaryl boronic acids, boronates, and trifluoroborates into the corresponding azides: substrate scope and limitations

Grimes, Kimberly D.; et al, Synthesis, 2010, (9), 1441-1448

合成路线：1 步

4595-59-9

1234903-01-5

反应条件：

1.1 Reagents: Sodium ascorbate , Sodium carbonate , Sodium azide Catalysts: L-Proline , Copper sulfate pentahydrate Solvents: Dimethylformamide , Water ; overnight, 85 °C

参考文献：

Biological evaluation of new mimetics of annonaceous acetogenins: Alteration of right scaffold by click linkage with aromatic functionalities

Liu, Yanghan; et al, European Journal of Medicinal Chemistry, 2014, 78, 248-258

合成路线：1 步

4595-59-9

1234903-01-5

反应条件：

1.1 Reagents: Sodium azide Solvents: Tetrahydrofuran ; rt; rt → 45 °C

参考文献：

Synthesis, spectral characterization and bio-activity of novel iminophosphorane derivatives of piperazine via Staudinger reaction

Chinnam, Sampath; et al, Pharma Chemica, 2012, 4(1), 288-296

合成路线：1 步