149082-03-1 (2-羟甲基-3,5-二甲基-4-硝基吡啶,3,5-Dimethyl-2-hydroxymethyl-4-nitropyridine)

快速询单

结构式：

2-羟甲基-3,5-二甲基-4-硝基吡啶MOL文件

CAS号：

149082-03-1

中文名称：

2-羟甲基-3,5-二甲基-4-硝基吡啶

英文名称：

3,5-Dimethyl-2-hydroxymethyl-4-nitropyridine

安全信息：

分子式：

C₈H₁₀N₂O₃

分子量：

182.176601886749

API：

omeprazole

2-羟甲基-3,5-二甲基-4-硝基吡啶(149082-03-1)名称与标识符

名称

中文别名：

2-羟甲基-3,5-二甲基-4-硝基吡啶;3,5-二甲基-4-硝基吡啶-2-甲醇;3,5-二甲基-4-硝基-2-吡啶甲醇;2-羟甲基-3,5-二甲基-4-硝基吡啶(奥美拉唑中间体);3,5-Dimethyl-4-nitro-2-pyridinemethanol 3,5-二甲基-4-硝基-2-吡啶甲醇;雷贝羟基物盐酸盐;牛磺脱氧胆酸;5-二甲基-4-硝基-2-吡啶甲醇;3,5-二甲基-2-羟甲基-4-硝基吡啶;3,5-二甲基-4-硝基-2-羟甲基吡啶;3,5-二甲基-4-硝基吡啶-2-甲醇,98%;3，5-二甲基-4- 硝基吡啶-2-甲醇;

英文别名：

(3,5-Dimethyl-4-nitropyridin-2-yl)methanol;3,5-Dimethyl-2-hydroxymethyl-4-nitropyridine;(3,5-dimethyl-4-nitro-2-pyridyl)-1-methanol;2-Hydroxymethyl-3,5-dimethyl-4-nitropyridine;3,5-Dimethyl-4-nitro-2-pyridinemethanol;3,5-Dimethyl-4-nitropyridine-2-methanol;2-(Hydroxymethyl)-3,5-dimethyl-4-nitropyridine;3,5-Dimethyl-4-nitro pyridin-2-methanol;3,5-(DIMETHYL-4-NITRO-2-PYRIDYL)METHANOL;(3,5-DIMETHYL-4-NITRO-2-PYRIDYL)METHAN-&;(3,5-dimethyl-4-nitro-2-pyridyl)-1-metha;2-hydromethyl-3,5-dimethyl-4-nitro-pyridine;(3,5-DIMETHYL-4-NITRO-2-PYRIDYL)METHAN-1-OL;(3,5-Dimethyl-4-nitro-2-pyridyl)-1-methanol, 97%;MFCD03426035;AKOS015891698;FT-0614682;DS-14790;AB14752;(3,5-Dimethyl-4-nitro-2-pyridinyl)methanol;SCHEMBL3089370;(3,5-Dimethyl-4-nitro-pyridin-2-yl)-methanol;2-(Hydroxymethyl)-3,5-dimethyl-4-nitropyridine;EN300-175309;2-HYDROMETHYL-3,5-DIMETHYL-4-NITROPYRIDINE;J-008549;CHEMBL4444883;KBCDOXSSYLFMHH-UHFFFAOYSA-N;A3269;DTXSID20398774;149082-03-1;2-hydroxymethyl-3,5dimethyl-4-nitropyridine;AC-8344;NS00122760;3,5-DIMETHYL-4-NITRO-2-HYDROXYMETHYL PYRIDINE;CS-W010746;2-Pyridinemethanol, 3,5-dimethyl-4-nitro-;SY038239;AM84451;D4026;A11239;

标识符

MDL：

MFCD03426035

InChIKey：

KBCDOXSSYLFMHH-UHFFFAOYSA-N

Inchi：

1S/C8H10N2O3/c1-5-3-9-7(4-11)6(2)8(5)10(12)13/h3,11H,4H2,1-2H3

SMILES：

OCC1C(C)=C(C(C)=CN=1)[N+](=O)[O-]

2-羟甲基-3,5-二甲基-4-硝基吡啶(149082-03-1)物化性质

实验特性

LogP : 1.62210
PSA : 78.94000
折射率 : 1.581
沸点 : 349℃ at 760 mmHg
熔点 : 66.0 to 70.0 deg-C
闪点 : 165.3°C
颜色与性状 : 黄色固体
溶解性 : 不能溶于水
密度 : 1.293

计算特性

精确分子量 : 182.06900
氢键供体数量 : 1
氢键受体数量 : 2
可旋转化学键数量 : 2
同位素质量 : 182.069
重原子数量 : 13
复杂度 : 192
同位素原子数量 : 0
确定原子立构中心数量 : 0
不确定原子立构中心数量 : 0
确定化学键立构中心数量 : 0
不确定化学键立构中心数量 : 0
共价键单元数量 : 1
疏水参数计算参考值（XlogP） : 0.6
互变异构体数量 : 无
表面电荷 : 0
拓扑分子极性表面积 : 78.9A^2

2-羟甲基-3,5-二甲基-4-硝基吡啶(149082-03-1)安全信息

符号： GHS07
WGK Germany： 3
安全术语： 6.1
安全说明： S26-S36
包装等级： III
包装类别： III
风险术语： R36/37/38
危险等级： 6.1
危险品标志： Xi
危险品运输编号： 2811
危害声明：H315,H319,H335
警示性声明：P261,P305+P351+P338
提示语：警告
储存条件： Store at 4°C,-4℃下存储更优
PackingGroup： III
危险类别码： 36/37/38
信号词： Warning
HazardClass： 6.1

2-羟甲基-3,5-二甲基-4-硝基吡啶(149082-03-1)国际标准相关数据

EINECS：

24879990

2-羟甲基-3,5-二甲基-4-硝基吡啶(149082-03-1)海关数据

海关编码：

2933399090

海关数据：

中国海关编码：

2933399090

概述：

2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

申报要素：

品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

Summary：

2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

2-羟甲基-3,5-二甲基-4-硝基吡啶(149082-03-1)生产方法和用途

用途：

用作药物中间体

2-羟甲基-3,5-二甲基-4-硝基吡啶(149082-03-1)推荐厂家更多厂家(37)

公司名称	手机号/电话	联系人	QQ	询单
湖北扬信医药科技有限公司	13092795037 0714-3996388	熊磊	3003473323	询单
上海吉至生化科技有限公司	18117592386 021-57481218	吉至试剂	3007522982	询单
湖北瑞诺医药科技有限公司	13165688766	汪经理	3008058303	询单
湖北扬信医药科技有限公司	18071854684 0714-3999001	程舒畅	2885409691	询单
JACS-郑州杰克斯化工产品有限公司	15981966935 0371-86259281	杰克斯JACS	893596907	询单
湖北云镁科技有限公司	18327059871 027-59206672	方经理	235010015	询单
深圳振强生物技术有限公司	13670046396 86-755-66853366	颜经理	2851296953	询单
上海瀚思化工有限公司	18939883912 021-34536277	顾经理	3003949364	询单
铼博（上海）生化科技有限公司	13311756052 021-60536361 13311756052 13311756131	张经理	2851717387	询单
上海一基实业有限公司	13311756131 021-60548336 QQ：2355265332 QQ:2851717387	胡经理	2355265332	询单

2-羟甲基-3,5-二甲基-4-硝基吡啶(149082-03-1)上下游

2,3,5-三甲基吡啶 2,3,4,6-四苄基-D-吡喃葡萄糖 4-硝基-2,3,5-三甲基吡啶氮氧化物

2-羟甲基-3,5-二甲基-4-硝基吡啶(149082-03-1)参考资料

Reaxys RN：

11080959

Beilstein：

MFCD03426035

PubChem CID：

4049415

2-羟甲基-3,5-二甲基-4-硝基吡啶(149082-03-1) MSDS

基础信息

3,5-Dimethyl-4-nitro-2-pyridinemethanol Revision number: 5
SAFETY DATA SHEET

Section 1. IDENTIFICATION
  Product name:        3,5-Dimethyl-4-nitro-2-pyridinemethanol

  Revision number:        5

Section 2. HAZARDS IDENTIFICATION
  GHS classification
  PHYSICAL HAZARDS        Not classified
  HEALTH HAZARDS
  Skin corrosion/irritation        Category 2
    Category 2A
  Serious eye damage/eye irritation
  ENVIRONMENTAL HAZARDS        Not classified
  GHS label elements, including precautionary statements
  Pictograms or hazard symbols
  Signal word        Warning
  Hazard statements        Causes skin irritation
    Causes serious eye irritation
  Precautionary statements:
    Wash hands thoroughly after handling.
  [Prevention]
    Wear protective gloves/eye protection/face protection.
    IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses,
  [Response]
    if present and easy to do. Continue rinsing.
    If eye irritation persists: Get medical advice/attention.
    IF ON SKIN: Gently wash with plenty of soap and water.
    If skin irritation occurs: Get medical advice/attention.
    Take off contaminated clothing and wash before reuse.

Section 3. COMPOSITION/INFORMATION ON INGREDIENTS
  Substance/mixture:        Substance
  Components:        3,5-Dimethyl-4-nitro-2-pyridinemethanol
  Percent:        >98.0%(GC)(T)
  CAS Number:        149082-03-1
  Synonyms:        2-(Hydroxymethyl)-3,5-dimethyl-4-nitropyridine
    C8H10N2O3
  Chemical Formula:

Section 4. FIRST AID MEASURES
  Inhalation:        Remove victim to fresh air and keep at rest in a position comfortable for breathing.
    Get medical advice/attention if you feel unwell.
  3,5-Dimethyl-4-nitro-2-pyridinemethanol

Section 4. FIRST AID MEASURES
  Skin contact:        Remove/Take off immediately all contaminated clothing. Gently wash with plenty of
    soap and water. If skin irritation or rash occurs: Get medical advice/attention.
  Eye contact:        Rinse cautiously with water for several minutes. Remove contact lenses, if present
    and easy to do. Continue rinsing. If eye irritation persists: Get medical
    advice/attention.
  Ingestion:        Get medical advice/attention if you feel unwell. Rinse mouth.
    A rescuer should wear personal protective equipment, such as rubber gloves and air-
  Protection of first-aiders:
    tight goggles.

Section 5. FIRE-FIGHTING MEASURES
  Suitable extinguishing        Dry chemical, foam, water spray, carbon dioxide.
  media:
  Specific hazards arising Take care as it may decompose upon combustion or in high temperatures to
  from the chemical:        generate poisonous fume.
  Precautions for firefighters: Fire-extinguishing work is done from the windward and the suitable fire-extinguishing
    method according to the surrounding situation is used. Uninvolved persons should
    evacuate to a safe place. In case of fire in the surroundings: Remove movable
    containers if safe to do so.
  Special protective        When extinguishing fire, be sure to wear personal protective equipment.
  equipment for firefighters:

Section 6. ACCIDENTAL RELEASE MEASURES
  Personal precautions,        Use personal protective equipment. Keep people away from and upwind of spill/leak.
  protective equipment and Entry to non-involved personnel should be controlled around the leakage area by
  emergency procedures: roping off, etc.
  Environmental precautions: Prevent product from entering drains.
  Methods and materials for Sweep dust to collect it into an airtight container, taking care not to disperse it.
  containment and cleaning Adhered or collected material should be promptly disposed of, in accordance with
  up: appropriate laws and regulations.

Section 7. HANDLING AND STORAGE
  Precautions for safe handling
  Technical measures:        Handling is performed in a well ventilated place. Wear suitable protective equipment.
    Prevent dispersion of dust. Wash hands and face thoroughly after handling.
    Use a local exhaust if dust or aerosol will be generated.
  Advice on safe handling: Avoid contact with skin, eyes and clothing.
  Conditions for safe storage, including any
  incompatibilities
  Storage conditions:        Keep container tightly closed. Store in a cool and dark place.
    Store away from incompatible materials such as oxidizing agents.
  Packaging material:        Comply with laws.

Section 8. EXPOSURE CONTROLS / PERSONAL PROTECTION
  Engineering controls:        Install a closed system or local exhaust as possible so that workers should not be
    exposed directly. Also install safety shower and eye bath.
  Personal protective equipment
  Respiratory protection: Dust respirator. Follow local and national regulations.
  Hand protection:        Protective gloves.
    Safety glasses. A face-shield, if the situation requires.
  Eye protection:
  Skin and body protection: Protective clothing. Protective boots, if the situation requires.

Section 9. PHYSICAL AND CHEMICAL PROPERTIES
  Physical state (20°C):        Solid
    Crystal- Powder
  Form:
  Colour:        White - Greyish yellow red
    No data available
  Odour:
  3,5-Dimethyl-4-nitro-2-pyridinemethanol

Section 9. PHYSICAL AND CHEMICAL PROPERTIES
  pH: No data available
  Melting point/freezing point:68°C
  Boiling point/range:        No data available
  Flash point:        No data available
  Flammability or explosive
  limits:
  Lower:        No data available
  Upper:        No data available
  Relative density:        No data available
  Solubility(ies):
  [Water]        No data available
  [Other solvents]
  Soluble:        Methanol

Section 10. STABILITY AND REACTIVITY
  Chemical stability:        Stable under proper conditions.
  Possibility of hazardous No special reactivity has been reported.
  reactions:
  Incompatible materials: Oxidizing agents
  Hazardous decomposition Carbon monoxide, Carbon dioxide, Nitrogen oxides (NOx)
  products:

Section 11. TOXICOLOGICAL INFORMATION
  Acute Toxicity:        No data available
  Skin corrosion/irritation: No data available
  Serious eye        No data available
  damage/irritation:
  Germ cell mutagenicity: No data available
  Carcinogenicity:
  IARC =        No data available
  NTP =        No data available
  Reproductive toxicity:        No data available

Section 12. ECOLOGICAL INFORMATION
  Ecotoxicity:
  Fish:        No data available
  Crustacea:        No data available
    No data available
  Algae:
  Persistence / degradability: No data available
    No data available
  Bioaccumulative
  potential(BCF):
  Mobility in soil
  Log Pow:        No data available
  Soil adsorption (Koc):        No data available
  Henry's Law        No data available
  constant(PaM3/mol):

Section 13. DISPOSAL CONSIDERATIONS
    Recycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material
    with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system.
    Observe all federal, state and local regulations when disposing of the substance.

Section 14. TRANSPORT INFORMATION
  Hazards Class:        Does not correspond to the classification standard of the United Nations
  UN-No:        Not listed
  3,5-Dimethyl-4-nitro-2-pyridinemethanol

Section 15. REGULATORY INFORMATION
  Safe management ordinance of dangerous chemical product (State Council announces on January 26, 2002
  and revised on February 16,2011): Safe use and production, the storage of a dangerous chemical, transport,
    loading and unloading were prescribed.

SECTION 16 - ADDITIONAL INFORMATION
N/A