960化工网

热搜：

Lactoyl-CoA 全氟丁基戊烷白叶藤碱全氟己基辛烷新白叶藤碱壳寡糖特色专题-生物多肽

1620458-09-4 (Zoliflodacin,Zoliflodacin)

结构式：

Zoliflodacin结构式图片|1620458-09-4结构式图片

ZoliflodacinMOL文件

CAS号：

1620458-09-4

中文名称：

Zoliflodacin

英文名称：

Zoliflodacin

分子式：

C₂₂H₂₂FN₅O₇

分子量：

487.437788486481

简介：

Zoliflodacin (ETX0914;AZD0914) 是一种新型的螺旋嘧啶三酮，细菌DNA促旋酶/拓扑异构酶抑制剂。Zoliflodacin 对革兰氏阳性和阴性生物具有有效的体外抗菌活性，对金黄色葡萄球菌的b>MIC90 值为0.25 μg/mL。

相关分类：

溶剂及有机化学品 > 有机化合物 > Organoheterocyclic compounds > Quinolines and derivatives > Hydroquinolines

Zoliflodacin(1620458-09-4)名称与标识符

名称

中文别名：

Zoliflodacin;

英文别名：

Zoliflodacin;

标识符

InChIKey：

ZSWMIFNWDQEXDT-ZESJGQACSA-N

Inchi：

1S/C22H22FN5O7/c1-8-7-33-21(32)28(8)17-12-4-11-5-22(18(29)24-20(31)25-19(22)30)16-10(3)34-9(2)6-27(16)14(11)13(23)15(12)35-26-17/h4,8-10,16H,5-7H2,1-3H3,(H2,24,25,29,30,31)/t8-,9+,10-,16+/m0/s1

SMILES：

FC1=C2C(C(=NO2)N2C(=O)OC[C@@H]2C)=CC2=C1N1C[C@@H](C)O[C@@H](C)[C@@H]1C1(C(NC(NC1=O)=O)=O)C2

Zoliflodacin(1620458-09-4)安全信息

储存条件： Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Zoliflodacin(1620458-09-4)推荐厂家更多厂家(9)

公司名称	手机号/电话	联系人	QQ	微信	询单
上海瀚思化工有限公司	18939883912 021-34536277	顾经理	3003949364		询单
北京索莱宝科技有限公司	18101056239 010-50973130	龚思雨	3193328036		询单
上海源叶生物科技有限公司	15026964105 15026964105	汤思磊	2881489226		询单
MedChemExpress（MCE 中国）	13611715263 021-58955995	MCE生命科学试剂	2881321772		询单
上海麦克林生化科技股份有限公司	15221275939 021-50706066	沈经理	269348414		询单
四川维克奇生物科技有限公司	13348961525	杨洋	2851167780		询单
上海源溪生物科技有限公司	13564518121	李经理	1724405207		询单
上海阿拉丁生化科技股份有限公司	13167063860 13167063860	阿拉丁	3004013043		询单

Zoliflodacin(1620458-09-4)相关文献

1. Repurposing drugs against the main protease of SARS-CoV-2: mechanism-based insights supported by available laboratory and clinical data
Sohini Chakraborti,Sneha Bheemireddy,Narayanaswamy Srinivasan Mol. Omics 2020 16 474
2. Late-stage functionalization of 5-nitrofurans derivatives and their antibacterial activities
Geshuyi Chen,Zhe Chang,Pei Yuan,Si Wang,Yongxiu Yang,Xiaolei Liang,Depeng Zhao RSC Adv. 2023 13 3204
3. The global antibiotic research and development partnership (GARDP): researching and developing new antibiotics to meet global public health needs
Laura J. V. Piddock Med. Chem. Commun. 2019 10 1227
4. Rational design, synthesis and testing of novel tricyclic topoisomerase inhibitors for the treatment of bacterial infections part 1
R. Kirk,A. Ratcliffe,G. Noonan,M. Uosis-Martin,D. Lyth,O. Bardell-Cox,J. Massam,P. Schofield,S. Hindley,D. R. Jones,J. Maclean,A. Smith,V. Savage,S. Mohmed,C. Charrier,A-M. Salisbury,E. Moyo,R. Metzger,N. Chalam-Judge,J. Cheung,N. R. Stokes,S. Best,M. Craighead,R. Armer,A. Huxley RSC Med. Chem. 2020 11 1366
5. Recent advances in the rational design and optimization of antibacterial agents
Jesse A. Jones,Kristopher G. Virga,Giuseppe Gumina,Kirk E. Hevener Med. Chem. Commun. 2016 7 1694
6. Benzothiazole DNA gyrase inhibitors and their conjugates with siderophore mimics: design, synthesis and evaluation
Martina Durcik,Cristina D. Cruz,Mariano Andrea Scorciapino,Janez Ila?,P?ivi Tammela,Matteo Ceccarelli,Lucija Peterlin Ma?i?,Tihomir Toma?i? RSC Adv. 2024 14 2905
7. Photoinduced [1,5]-hydride shift triggered cyclization
Nadezhda S. Baleeva,Alexander Yu. Smirnov,Elvira R. Zaitseva,Dmitrii S. Ivanov,Anatolii I. Sokolov,Andrey A. Mikhaylov,Ivan N Myasnyanko,Mikhail S. Baranov New J. Chem. 2023 47 12536
8. Improved broad-spectrum antibiotics against Gram-negative pathogens via darobactin biosynthetic pathway engineering
Sebastian Gro?,Fabian Panter,Domen Pogorevc,Carsten E. Seyfert,Selina Deckarm,Chantal D. Bader,Jennifer Herrmann,Rolf Müller Chem. Sci. 2021 12 11882
9. Oxazolidinones as versatile scaffolds in medicinal chemistry
Guilherme Felipe Santos Fernandes,Cauê Benito Scarim,Seong-Heun Kim,Jingyue Wu,Daniele Castagnolo RSC Med. Chem. 2023 14 823
10. A call for action to the biomaterial community to tackle antimicrobial resistance
Thomas J. Hall,Victor M. Villapún,Owen Addison,Mark A. Webber,Morgan Lowther,Sophie E. T. Louth,Sophie E. Mountcastle,Mathieu Y. Brunet,Sophie C. Cox Biomater. Sci. 2020 8 4951

目录

相关化合物

79888-41-8(3-（5-丙基-1,3,4-噻二唑-2-基）氨基甲酰基丙酸) 799283-94-6(3-(4-methoxyphenyl)benzenesulfonyl chloride) 799-87-1(对苯二酚硫酸钾) 800401-52-9(5-bromo-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid) 800401-92-7(800401-92-7) 800394-83-6(1-[3-(4-oxocyclohexa-2,5-dien-1-ylidene)-4H-pyrido[2,3-b]pyrazin-6-yl]-3-prop-2-enylthiourea) 80096-57-7(C-(1,2,3,4-TETRAHYDRO-NAPHTHALEN-1-YL)-METHYLAMINE HYDROCHLORIDE) 79373-33-4(双环醇)

问答

960化工网为您提供Zoliflodacin专业化合物百科信息，包括中文名，英文名，分子式，分子量，以及该化合物的CasNo.1620458-09-4,相关理化性质;并提供了优质生产厂家信息包括厂家名称和联系方式等。 WAP版:1620458-09-4 国际站:1620458-09-4

© 2008-2025 南京九六零网络科技有限公司版权所有营业执照公示

粤ICP备2021105330号-3 公安机关备案号32010502010001 苏公网安备32011202001462号法律声明