20962-92-9 (N-烯丙基吩噻嗪,N-Allylphenothiazine)

_87%

反应条件：

1.1 Reagents: Potassium hydroxide Solvents: Dimethylformamide ; 30 min, rt
1.2 rt; 20 h, rt

参考文献：

Phenanthroimidazole/carbazole and phenanthroimidazole/phenothiazine hybrids with alkoxyorganosilane functional groups as blue emitting materials

Zhang, Chen; Su, Ruige; Guo, Yongchun; Li, Debao; Zhao, Jiaqin; et al, Journal of Molecular Structure, 2022, 1262,

合成路线：1 步

_94%

反应条件：

1.1 Reagents: Ammonium chloride Solvents: Glucose , Urea ; rt; 75 - 90 min, 78 - 80 °C

参考文献：

Sugar-urea-salt eutectic mixture as an efficient green solvent for N-alkylation of heterocyclic secondary amines

Kumar, Koravangala S. Vinay; Swaroop, Toreshettahally R.; Ravi Singh, Krishna; Rangappa, Kanchugarakoppal S.; Sadashiva, Maralinganadoddi P., Chemical Data Collections, 2020, 29,

合成路线：1 步

107-18-6

_36%

反应条件：

1.1 Catalysts: Propylphosphonic anhydride Solvents: Toluene , 1,4-Dioxane ; rt; rt → 0 °C; 10 min, 0 °C
1.2 16 h, 130 °C

参考文献：

A Novel N-Benzylation of Phenothiazine with Benzyl Alcohols Activated by n-Propylphosphonic Acid Anhydride (T3P)

Levi, Lucilla; Scheuren, Sven; Mueller, Thomas J. J., Synthesis, 2014, 46(22), 3059-3066

合成路线：1 步

591-87-7

_66%

反应条件：

1.1 Catalysts: Triphenylphosphine , Palladium diacetate Solvents: Water ; 2 h, reflux

参考文献：

Simple palladium-catalyzed C-N bond formation for poor nucleophilicity of aminonaphthalenes

Shue, Yi-Jen; Yang, Shyh-Chyun, Applied Organometallic Chemistry, 2011, 25(12), 883-890

合成路线：1 步

109-64-8

_70%

反应条件：

1.1 Reagents: Sodium hydroxide Catalysts: Tetrabutylammonium bromide Solvents: Methyl isobutyl ketone , Water ; 24 h, rt; 24 h, reflux

参考文献：

Walking on the surface of phenothiazines: a combined experimental and theoretical approach

Porumb, Dan; Lovasz, Tamas; Rachita, Gratiana; Cristea, Castelia; Gaina, Luiza; et al, Revue Roumaine de Chimie, 2010, 55(11-12), 879-884

合成路线：1 步

591-87-7

_70%

反应条件：

1.1 Catalysts: Triphenylphosphine , Platinum acetylacetonate Solvents: Water ; 3 h, reflux

参考文献：

Platinum-catalyzed allylation of aminonaphthalenes with allylic acetates in water

Gan, Kim-Hong; Jhong, Ciou-Jyu; Shue, Yi-Jen; Yang, Shyh-Chyun, Tetrahedron, 2008, 64(40), 9625-9629

合成路线：1 步

591-87-7

_32%

反应条件：

1.1 Catalysts: Tris(4-chlorophenyl)phosphine , Platinum acetylacetonate Solvents: Benzene ; 3 h, reflux

参考文献：

Platinum-catalyzed allylation of aminonaphthalenes with allylic acetates

Yang, Shyh-Chyun; Feng, Wei-Hao; Gan, Kim-Hong, Tetrahedron, 2006, 62(15), 3752-3760

合成路线：1 步

107-18-6

_76%

反应条件：

1.1 Reagents: Titanium isopropoxide , Triphenylphosphine Catalysts: Palladium diacetate Solvents: Benzene ; 3 h, reflux; cooled

参考文献：

Palladium-catalyzed allylation of acidic and less nucleophilic anilines using allylic alcohols directly

Hsu, Yi-Chun; Gan, Kim-Hong; Yang, Shyh-Chyun, Chemical & Pharmaceutical Bulletin, 2005, 53(10), 1266-1269

合成路线：1 步

_62%

反应条件：

1.1 Reagents: Tetrabutylammonium bromide

参考文献：

Monomeric and Polymeric Phenothiazine Photosensitizers for Photoinitiated Cationic Polymerization

Gomurashvili, Zaza; Crivello, James V., Macromolecules, 2002, 35(8), 2962-2969

合成路线：1 步

_80%